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| | 5-OMe-UDP trisodiuM salt Basic information |
| Product Name: | 5-OMe-UDP trisodiuM salt | | Synonyms: | 5-OMe-UDP trisodiuM salt;5-Methoxyuridine 5'-diphosphate trisodium salt;Uridine 5'-(trihydrogen diphosphate), 5-methoxy-;5 OMe UDP trisodium salt,5OMeUDP trisodium salt;5-Methoxyuridine 5'-(trihydrogen diphosphate) | | CAS: | 1207530-98-0 | | MF: | C10H16N2O13P2 | | MW: | 434.19 | | EINECS: | | | Product Categories: | Potent P2Y6 agonist. | | Mol File: | 1207530-98-0.mol |  |
| | 5-OMe-UDP trisodiuM salt Chemical Properties |
| storage temp. | Store at -20°C | | form | Powder | | Water Solubility | Soluble in water (supplied pre-dissolved at a concentration of 10mM) |
| | 5-OMe-UDP trisodiuM salt Usage And Synthesis |
| Description | Potent P2Y6agonist (EC50= 0.08μM). Displays greater potency at P2Y6than UDP (EC50= 0.14μM). | | Uses | 5-OMe-UDP (5-methoxyuridine 5'-trihydrogen diphosphate) is a P2Y6 receptor agonist (EC50=0.08 μM). 5-OMe-UDP activates the P2Y6 receptor by binding to it, which triggers signaling pathways within the cell. This activation can lead to an increase in intracellular calcium ion concentration, which in turn regulates cellular function. The methoxy groups of 5-OMe-UDP provide additional activity and selectivity, contributing to the binding of 5-OMe-UDP to the P2Y6 receptor. 5-OMe-UDP can be used to study diseases related to P2Y6 receptor function, such as diabetes, inflammatory bowel disease, Alzheimer's disease, etc[1]. | | IC 50 | P2Y6 Receptor: 0.08 μM (EC50) | | References | [1] Ginsburg-Shmuel T, et al. UDP made a highly promising stable, potent, and selective P2Y6-receptor agonist upon introduction of a boranophosphate moiety[J]. Bioorganic & medicinal chemistry, 2012, 20(18): 5483-5495. DOI:10.1016/j.bmc.2012.07.042 |
| | 5-OMe-UDP trisodiuM salt Preparation Products And Raw materials |
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