- UDP-GlcNAc.2Na
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2020-03-26
- CAS:91183-98-1
- Min. Order: 10mg
- Purity: 97%HPLC
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| | UDP-alpha-D-N-acetylglucosamine, disodium salt Basic information |
| | UDP-alpha-D-N-acetylglucosamine, disodium salt Chemical Properties |
| storage temp. | -20°C | | solubility | Methanol (Slightly, Heated), Water (Slightly) | | form | Solid | | color | White to off-White | | biological source | bakers yeast | | Water Solubility | water: 50mg/mL | | InChIKey | BREKHDYLBRBJNL-ALFVBSQCNA-N | | SMILES | O[C@@H]1[C@@H]([C@@H](COP(O)(=O)OP(O)(=O)O[C@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2NC(=O)C)O[C@H]1N1C=CC(=O)NC1=O)O.[NaH] |&1:1,2,3,14,16,19,21,23,29,r| |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 22-26-36 | | WGK Germany | 3 | | HS Code | 29349990 | | Storage Class | 11 - Combustible Solids |
| | UDP-alpha-D-N-acetylglucosamine, disodium salt Usage And Synthesis |
| Chemical Properties | White to off-white crystalline powder | | Uses | Uridine-5'-diphospho-N-acetylglucosamine sodium salt is used as a chemical reagent in studies relating to the synthesis of immunogens. | | Uses | GlcNAc transferase substrate | | Uses | Uridine 5′-diphospho-N-acetylglucosamine (UDP-GlcNAc) sodium salt has been used:
- as a component of reaction cocktail in endoplasmic reticulum to Golgi transport assay
- as a reference standard for the quantification of UDP-GlcNAc in liver tissues using high-performance liquid chromatography (HPLC)
- in testing the glycosylation activity of O-GlcNAc transferase (OGT) against peptide substrate
| | General Description | Uridine 5′-diphospho-N-acetylglucosamine (UDP-GlcNAc) is a nucleotide sugar. It is synthesized from glucose via the hexosamine biosynthetic pathway (HBP). UDP-GlcNAc is transported actively into Golgi, nucleotide sugar transporter (NST). The levels of UDP-GlcNAc is modulated by the concentration of nutrients exposed to the cell. | | Biochem/physiol Actions | Uridine 5′-diphospho-N-acetylglucosamine (UDP-GlcNAc) is a sugar donor and aids in the endomembrane glycosylation of endoplasmic reticulum and Golgi. The decreased levels of UDP-GlcNAc has an influence on the normal cellular proliferation and apoptosis. UDP-GlcNAc elicits feedback inhibition of the enzyme glutamine:fructose-6-phosphate amidotransferase (GFAT). |
| | UDP-alpha-D-N-acetylglucosamine, disodium salt Preparation Products And Raw materials |
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