13(S),14(S)-epoxy Fluprostenol isopropyl ester

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Company Name: Shanghai Hongye Biotechnology Co. Ltd  
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Company Name: ChemeGen(Shanghai) Biotechnology Co.,Ltd.  
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13(S),14(S)-epoxy Fluprostenol isopropyl ester Basic information
Product Name:13(S),14(S)-epoxy Fluprostenol isopropyl ester
Synonyms:13(S),14(S)-epoxy Fluprostenol isopropyl ester
CAS:
MF:C26H35F3O7
MW:516.5471096
EINECS:
Product Categories:
Mol File:Mol File
13(S),14(S)-epoxy Fluprostenol isopropyl ester Structure
13(S),14(S)-epoxy Fluprostenol isopropyl ester Chemical Properties
solubility DMF: 30 mg/ml
DMSO: 5 mg/ml
Ethanol: 30 mg/ml
Ethanol: PBS(pH 7.2) (1:1): 0.5 mg/ml
Safety Information
MSDS Information
13(S),14(S)-epoxy Fluprostenol isopropyl ester Usage And Synthesis
DescriptionFluprostenol isopropyl ester (Item No. 16769) is a potent F-series prostaglandin receptor agonist prodrug that finds clinical use as an ocular hypotensive agent for the treatment of glaucoma.1,2 13,14-epoxy Fluprostenol isopropyl ester (Item No. 13679) is an impurity generated in the production of fluprostenol isopropyl ester. This product is a chiral enantiomer of the epoxide. The pharmacology of 13(S),14(S)-epoxy fluprostenol isopropyl ester has not been studied extensively to date.WARNING This product is not for human or veterinary use.
References[1] Travoprost[J]. Reactions Weekly, 2009, 22 1: 40-41. DOI: 10.2165/00128415-200912530-00134
[2] M. HELLBERG. Preclinical efficacy of travoprost, a potent and selective FP prostaglandin receptor agonist.[J]. Journal of Ocular Pharmacology and Therapeutics, 2001, 9 1: 421-432. DOI: 10.1089/108076801753266802
13(S),14(S)-epoxy Fluprostenol isopropyl ester Preparation Products And Raw materials
Tag:13(S),14(S)-epoxy Fluprostenol isopropyl ester Related Product Information
15-Keto Travoprost 5,6-trans Travoprost 5-Heptenoic acid, 7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(2R,3R)-3-[(1S)-1-hydroxy-2-[3-(trifluoromethyl)phenoxy]ethyl]-2-oxiranyl]cyclopentyl]-, 1-methylethyl ester, (5Z)- 15(S)-Fluprostenol isopropyl ester 5-Heptenoic acid, 7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(2R)-3-[(1S)-1-hydroxy-2-[3-(trifluoromethyl)phenoxy]ethyl]-2-oxiranyl]cyclopentyl]-, 1-methylethyl ester, (5Z)-