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| 3-Ethoxy-4-Methoxy-alpha-[(Methylsulfonyl)Methyl]-benzeneMethanaMine Basic information |
Product Name: | 3-Ethoxy-4-Methoxy-alpha-[(Methylsulfonyl)Methyl]-benzeneMethanaMine | Synonyms: | Apremilast Impurity 42;3-Ethoxy-4-methoxy-α-[(methylsulfonyl)methyl]benzenemethanamine;1-(3-Ethoxy-4-methoxyphenyl)-2-
(methylsulofonyl)ethan-1-amine;Apremilast int;1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethan-1-amine;1-(3-Ethoxy-4-methoxy-phenyl)-2-methanesulfonyl-ethylamine;1.1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethan-1-amine;2-(3-ethoxy-4-methoxyphenyl)-1-(methylsulfonyl)eth-2-ylamine | CAS: | 253168-94-4 | MF: | C12H19NO4S | MW: | 273.35 | EINECS: | 807-312-3 | Product Categories: | apremilast intermediates | Mol File: | 253168-94-4.mol | ![3-Ethoxy-4-Methoxy-alpha-[(Methylsulfonyl)Methyl]-benzeneMethanaMine Structure](CAS/20150408/GIF/253168-94-4.gif) |
| 3-Ethoxy-4-Methoxy-alpha-[(Methylsulfonyl)Methyl]-benzeneMethanaMine Chemical Properties |
Melting point | 120 °C | Boiling point | 469.6±45.0 °C(Predicted) | density | 1.195±0.06 g/cm3(Predicted) | storage temp. | Keep in dark place,Inert atmosphere,Room temperature | solubility | Chloroform (Slightly, Heated, Sonicated), DMSO (Slightly, Heated), Methanol (Slightly) | form | Solid | pka | 6.84±0.10(Predicted) | color | White to Off-White | InChI | InChI=1S/C12H19NO4S/c1-4-17-12-7-9(5-6-11(12)16-2)10(13)8-18(3,14)15/h5-7,10H,4,8,13H2,1-3H3 | InChIKey | BXUJVINGXQGNFD-UHFFFAOYSA-N | SMILES | C1(C(CS(C)(=O)=O)N)=CC=C(OC)C(OCC)=C1 |
| 3-Ethoxy-4-Methoxy-alpha-[(Methylsulfonyl)Methyl]-benzeneMethanaMine Usage And Synthesis |
Uses | 1-(3-Ethoxy-4-methoxy-phenyl)-2-methanesulfonylethylamine is used in the enantioselective synthesis of Apremilast (A729700) aminosulfone using catalytic asymetric hydrogenation. Apremilast EP Impurity H |
| 3-Ethoxy-4-Methoxy-alpha-[(Methylsulfonyl)Methyl]-benzeneMethanaMine Preparation Products And Raw materials |
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