胆甾烯基豆蔻酸酯
| 中文名称 | 胆甾烯基豆蔻酸酯 |
|---|---|
| 中文同义词 | 肉豆蔻酸胆固醇酯;胆固醇肉豆蔻酸酯,液晶;肉豆蔻酸胆固醇;胆固醇豆蔻酸酯;豆蔻酸胆固醇酯;胆固醇肉豆蔻酸?, >98%;胆甾烯基豆蔻酸酯;胆甾醇豆蔻酸酯 |
| 英文名称 | Cholesteryl myristate |
| 英文同义词 | MYRISTIC ACID CHOLESTEROL ESTER;Cholesterol myristate, >98%;(3β)-cholest-5-en-3-yltetradecanoate;3β-tetradecanoyloxycholest-5-ene;Cholest-5-en-3-ol (3beta)-, tetradecanoate;Cholest-5-en-3-yl myristate;Cholestryl myristate;CM |
| CAS号 | 1989-52-2 |
| 分子式 | C41H72O2 |
| 分子量 | 597.01 |
| EINECS号 | 217-867-8 |
| 相关类别 | 合成;有机中间体;Steroids;Cholesteryl Compounds (Liquid Crystals);Functional Materials;Liquid Crystals & Related Compounds |
| Mol文件 | 1989-52-2.mol |
| 结构式 |  |
胆甾烯基豆蔻酸酯 性质
| 熔点 | 84 °C |
|---|---|
| 沸点 | 589.77°C (rough estimate) |
| 密度 | 0.9309 (rough estimate) |
| 折射率 | 1.5250 (estimate) |
| 储存条件 | Sealed in dry,2-8°C |
| 溶解度 | 氯仿（微溶）、己烷（微溶） |
| 形态 | 结晶固体 |
| 颜色 | 白色至米白色 |
| LogP | 16.656 (est) |
| CAS 数据库 | 1989-52-2(CAS DataBase Reference) |
| NIST化学物质信息 | Cholesteryl myristate(1989-52-2) |
| EPA化学物质信息 | Cholest-5-en-3-ol (3.beta.)-, tetradecanoate (1989-52-2) |
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Human Endogenous Metabolite
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Mesenchymal stem cells (MSCs) transfected by the Id1 promoter reporter construct, cholesterol myristate increases the activity of Id1 promoter. Cholesterol myristate inhibits the apoptosis of MSCs induced by serum-free. Cholesterol myristate increases the expression of Id1 and its target gene bcl-x/l in MSCs treated with serum-free. Moreover, noggin, a BMP antagonist, reduces the anti-apoptotic effects of cholesterol myristate. Cholesterol myristate inhibits the apoptosis of PC12 cells induced in serum-free condition. Cholesterol myristate significantly increases the expression of BMP4, BMPRIA, p-Smad1/5/8, Id1 and its antiapoptotic target gene Bcl-xL in PC12 cells treated in serum-free condition.