|
|
| Product Name: | 2-Chloroethyl carbamate | | Synonyms: | B-CHLOROETHYL CARBAMATE;BETA-CHLOROETHYLURETHANE;BETA-CHLOROETHYL CARBAMATE;2-CHLOROETHYL CARBAMATE;2-CHLOROETHYL CARBAMATE 97%;Carbamic acid, beta-chloroethyl ester;carbamicacid,2-chloroethylester;carbamicacid,beta-chloroethylester | | CAS: | 2114-18-3 | | MF: | C3H6ClNO2 | | MW: | 123.54 | | EINECS: | 218-310-1 | | Product Categories: | | | Mol File: | 2114-18-3.mol |  |
| | 2-Chloroethyl carbamate Chemical Properties |
| | 2-Chloroethyl carbamate Usage And Synthesis |
| Synthesis | Using chloroethanol and a carbamylated reagent as raw materials, 2-chloroethylcarbamate is produced in a one-step reaction in the presence of a catalyst. The specific process is as follows:
In a 1000ml four-necked round-bottom flask equipped with a reflux condenser and an electric stirrer, 563.5g (7mol) of chloroethanol is added, the stirring is started, and the temperature is raised. When the temperature reaches 90℃, 307.5g of urea nitrate (2.5mol) and 172.5g of sodium nitrite (1mol) are added. The reaction is carried out between 80-125℃ for 4 hours. Excess chloroethanol is distilled off, and 500ml of diethyl ether is added to the residue. After thorough stirring, the mixture is filtered, and the diethyl ether is distilled off. 2-chloroethylcarbamate is then distilled off under reduced pressure, yielding 90g, with a yield of 30%.
 | | Uses | 2-Chloroethylcarbamate, also known as chloroethyl carbamate, is a synthetic intermediate of carbachol. Carbachol is a complete cholinergic drug, which is significantly effective in treating glaucoma and postpartum abdominal distension and urinary retention. |
| | 2-Chloroethyl carbamate Preparation Products And Raw materials |
|