| Company Name: |
BOC Sciences |
| Tel: |
1-631-485-4226; 16314854226 |
| Email: |
info@bocsci.com |
GBR 12783 dihydrochloride manufacturers
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| | GBR 12783 dihydrochloride Basic information |
| Product Name: | GBR 12783 dihydrochloride | | Synonyms: | GBR 12921 dihydrochloride;Piperazine,1-[2-(diphenylmethoxy)ethyl]-4-(3-phenyl-2-propenyl)-,dihydrochloride;1-(2-(Benzhydryloxy)ethyl)-4-cinnamylpiperazine dihydrochloride;GBR 12783 dihydrochloride, 10 mM in DMSO | | CAS: | 67469-75-4 | | MF: | C28H33ClN2O | | MW: | 449.04 | | EINECS: | | | Product Categories: | | | Mol File: | 67469-75-4.mol |  |
| | GBR 12783 dihydrochloride Chemical Properties |
| storage temp. | Desiccate at -20°C | | solubility | Water:4.86(Max Conc. mg/mL);10.01(Max Conc. mM) | | form | Powder | | color | White to off-white | | Water Solubility | Soluble to 10 mM in water with gentle warming |
| | GBR 12783 dihydrochloride Usage And Synthesis |
| Uses | GBR 12783 Dihydrochloride is a potent, selective dopamine uptake inhibitor. | | in vivo | GBR 12783 (10 mg/kg; intraperitoneal injection; for 100 minutes; male Sprague-Dawley rats) treatment reinforces specifically dopamine transmission only at synapses instantaneously active, increases hippocampal ACh release and improves memory performance in a passive avoidance task[1]. | Animal Model: | Male Sprague-Dawley rats (180-200 g)[1] | | Dosage: | 10 mg/kg | | Administration: | Intraperitoneal injection; for 100 minutes | | Result: | For a moderate electric shock intensity (0.4 mA), improveed retention performance, increased hippocampal acetylcholine release in vivo.
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| | storage | Desiccate at -20°C |
| | GBR 12783 dihydrochloride Preparation Products And Raw materials |
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