m-PEG4-t-butyl ester

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m-PEG4-t-butyl ester manufacturers

  • m-PEG4-Boc
  • m-PEG4-Boc pictures
  • $1.60
  • 2026-08-25
  • CAS:883554-11-8
  • Min. Order: 1kg
  • Purity: 99%
  • Supply Ability: 100kg
  • m-PEG4-Boc
  • m-PEG4-Boc pictures
  • 2026-05-11
  • CAS:883554-11-8
  • Purity:
  • Supply Ability: 10g
m-PEG4-t-butyl ester Basic information
Product Name:m-PEG4-t-butyl ester
Synonyms:m-PEG4-t-butyl ester;mPEG4-CH2CH2COOtBu;tert-Butyl 3-{2-[2-(2-methoxyethoxy)ethoxy]ethoxy}propionate/m-PEG4-t-butyl ester;m-PEG4-Boc;4,7,10,13-Tetraoxatetradecanoic acid, 1,1-dimethylethyl ester;mPEG3-CH2CH2COOtBu;tert-butyl 2,5,8,11-tetraoxatetradecan-14-oate;m-PEG4-COOtBu
CAS:883554-11-8
MF:C14H28O6
MW:292.37
EINECS:
Product Categories:
Mol File:883554-11-8.mol
m-PEG4-t-butyl ester Structure
m-PEG4-t-butyl ester Chemical Properties
storage temp. Storage temp. 2-8°C
form Liquid
color Colorless to off-white
Safety Information
MSDS Information
m-PEG4-t-butyl ester Usage And Synthesis
Descriptionm-PEG4-t-butyl ester is a PEG linker containing a t-butyl ester. The t-butyl protected carboxyl group can be deprotected under acidic conditions. The hydrophilic PEG spacer increases solubility in aqueous media.
Usesm-PEG4-Boc is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. m-PEG4-Boc is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[2].
IC 50PEGs; Cleavable Linker
References[1] Hervé Bouchard, et al. Peptidic linkers and cryptophycin conjugates, useful in therapy, and their preparation. WO2018206635A1.
[2] Peter Madsen, et al. Protease stabilized, pegylated insulin analogues. WO2009010428A1.
m-PEG4-t-butyl ester Preparation Products And Raw materials
Tag:m-PEG4-t-butyl ester(883554-11-8) Related Product Information
3,6,9,12,15-Pentaoxaheptadecane-1,17-diyl bis-amine 2,5,8,11,14-pentaoxahexadecan-16-oic acid Amino-PEG11-Amine O,O′-Bis(2-aMinoethyl)polyethylene Glycol Amino-PEG9-Amine [2-[2-[2-[2-(2-Methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]acetic acid 3,6,9,12,15,21,24,27,30-Decaoxadotriacontane-1,32-diaMine 1,14-diamino-3,6,9,12-tetraoxatetradecane 3,6,9,12,15,18,21,24,27,30-Decaoxahentriacontanoic acid mPEG15-acetic acid mPEG6-CH2COOH 3,6,9,12,15,18-Hexaoxaeicosane-1,20-diamine 3,6,9-trioxaundecamethylenediamine 3,6,9,12,15,18,21,24,27-Nonaoxaoctacosanoic acid 3,6,9,1,15,18,21,24-Octaoxahexacosane-1-26-diaMi tert-Butyl acetate Ethanol, 2-[2-(2-hydroxyethoxy)ethoxy]-, 1-(4-Methylbenzenesulfonate)