2,5,8,11,14-pentaoxahexadecan-16-oic acid

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2,5,8,11,14-pentaoxahexadecan-16-oic acid manufacturers
2,5,8,11,14-pentaoxahexadecan-16-oic acid Basic information
Product Name:2,5,8,11,14-pentaoxahexadecan-16-oic acid
Synonyms:m-PEG5-CH3COOH;2,5,8,11,14-pentaoxahexadecan-16-oic acid;3,6,9,12,15-Pentaoxahexadecanoic acid;Einecs 240-163-7;Methyl-PEG4-CH2COOH;CAS_16024-66-1;mPEG4-acetic acid;2,5,8,11,14-Pentaoxahexadecan-16-sure
CAS:16024-66-1
MF:C11H22O7
MW:266.29
EINECS:2401637
Product Categories:
Mol File:16024-66-1.mol
2,5,8,11,14-pentaoxahexadecan-16-oic acid Structure
2,5,8,11,14-pentaoxahexadecan-16-oic acid Chemical Properties
Boiling point 379.6±32.0 °C(Predicted)
density 1.125±0.06 g/cm3(Predicted)
storage temp. Storage temp. 2-8°C
solubility DMSO : 100 mg/mL (375.53 mM; Need ultrasonic)
pka3.39±0.10(Predicted)
form Liquid
color Colorless to light yellow
Safety Information
MSDS Information
2,5,8,11,14-pentaoxahexadecan-16-oic acid Usage And Synthesis
Descriptionm-PEG5-CH2COOH is a PEG linker containing a terminal carboxylic acid. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The hydrophilic PEG spacer increases solubility in aqueous media.
Usesm-PEG4-CH2COOH is a PEG-based based PROTAC linker can be used in the synthesis of PROTACs.
IC 50PEGs
References[1] TaoDeng, et al. Monodisperse oligoethylene glycols modified Propofol prodrugs. Bioorganic & Medicinal Chemistry Letters.
2,5,8,11,14-pentaoxahexadecan-16-oic acid Preparation Products And Raw materials
Raw materialsTetraethyleneglycol monomethyl ether-->1-(2-Chloro-ethoxy)-2-(2-methoxy-ethoxy)-ethane-->Pentaethylene glycol monomethyl ether-->Bromoacetic acid-->tetraethylene glycol
Tag:2,5,8,11,14-pentaoxahexadecan-16-oic acid(16024-66-1) Related Product Information
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