PEG3-bis-(ethyl phosphonate)

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PEG3-bis-(ethyl phosphonate) Basic information
Product Name:PEG3-bis-(ethyl phosphonate)
Synonyms:PEG3-bis-(ethyl phosphonate);Phosphonic acid, P,P'-[oxybis(2,1-ethanediyloxy-2,1-ethanediyl)]bis-, P,P,P',P'-tetraethyl ester;Diethyl-[oxybis(2,1-ethanediyloxy-2,1-ethanediyl)]bis-phosphonate;P,P,P′,P′-Tetraethyl P,P′-[oxybis(2,1-ethanediyloxy-2,1-ethanediyl)]bis[phosphon…
CAS:160625-24-1
MF:C16H36O9P2
MW:434.4
EINECS:
Product Categories:
Mol File:160625-24-1.mol
PEG3-bis-(ethyl phosphonate) Structure
PEG3-bis-(ethyl phosphonate) Chemical Properties
Boiling point 510.5±45.0 °C(Predicted)
density 1.126±0.06 g/cm3(Predicted)
Safety Information
MSDS Information
PEG3-bis-(ethyl phosphonate) Usage And Synthesis
DescriptionPEG3-bis-(ethyl phosphonate) is a PEG linker with two ethyl phosphonate end groups. The hydrophilic PEG linker increases the water solubility of the compound in aqueous media.
UsesPEG3-bis-(ethyl phosphonate) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
IC 50PEGs
References[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
PEG3-bis-(ethyl phosphonate) Preparation Products And Raw materials
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PEG5-bis-(ethyl phosphonate) PEG3-bis(phosphonic acid) PEG3-bis(phosphonic acid diethyl ester) (2-{2-[2-(Diethoxy-phosphoryl)-ethoxy]-ethoxy}-ethyl)-phosphonic acid Diethyl ester m-PEG4-phosphonic acid ethyl ester Propargyl-PEG3-phosphonic acid ethyl ester