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BOC Sciences |
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MitoTEMPOL manufacturers
- MitoTEMPOL
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- $479.00
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2026-07-27
- CAS:1101113-39-6
- Purity: 98.06%
- Supply Ability: 10g
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| | MitoTEMPOL Basic information |
| Product Name: | MitoTEMPOL | | Synonyms: | MitoTEMPOL;Triphenyl(5-((2,2,6,6-tetramethyl-1-(l1-oxidaneyl)piperidin-4-yl)oxy)pentyl)phosphonium bromide;MitoTEMPOL, mitochondria-targeted antioxidant agent | | CAS: | 1101113-39-6 | | MF: | C32H42BrNO2P* | | MW: | 583.559 | | EINECS: | | | Product Categories: | | | Mol File: | 1101113-39-6.mol |  |
| | MitoTEMPOL Chemical Properties |
| storage temp. | Store at -20°C | | solubility | DMF: 50 mg/ml; DMSO: 50 mg/ml; Ethanol: 50 mg/ml; PBS (pH 7.2): 10 mg/ml | | form | A solid | | color | Brown to orange |
| | MitoTEMPOL Usage And Synthesis |
| Description | MitoTEMPOL is a mitochondria-targeting superoxide dismutase mimetic that reduces mitochondrial O2- to H2O2. Like the related compound MitoTEMPO , MitoTEMPOL combines an antioxidant moiety (here, TEMPOL, also known as 4-hydroxy-TEMPO) with the lipophilic cation triphenylphosphonium, which allows it to pass through lipid bilayers and accumulate in mitochondria. MitoTEMPOL has been used to elucidate the role of mitochondria-derived superoxide in mitochondrial, cellular, and whole animal signaling. | | Uses | MitoTEMPOL is a a mitochondria-targeted nitroxide that reduces mitochondrial O2-to H2O2[1]. | | References | [1] Trnka J, et al. A mitochondria-targeted nitroxide is reduced to its hydroxylamine by ubiquinol in mitochondria. Free Radic Biol Med. 2008;44(7):1406-1419. DOI:10.1016/j.freeradbiomed.2007.12.036 |
| | MitoTEMPOL Preparation Products And Raw materials |
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