| Company Name: |
BOC Sciences |
| Tel: |
+1-631-485-4226 |
| Email: |
inquiry@bocsci.com |
Melphalan Flufenamide manufacturers
- Melflufen
-
- $1630.00
-
2026-07-17
- CAS:380449-51-4
- Purity: 97.05%
- Supply Ability: 10g
|
| | Melphalan Flufenamide Basic information |
| Product Name: | Melphalan Flufenamide | | Synonyms: | Melphalan Flufenamide;Prodrug J-1;Prodrug J-1, Melflufen, Melphalan flufenamide;L-Phenylalanine, 4-[bis(2-chloroethyl)amino]-L-phenylalanyl-4-fluoro-, ethyl ester;Venadaparib Impurity 58;Ethyl (S)-2-((S)-2-amino-3-(4-(bis(2-chloroethyl)amino)phenyl)propanamido)-3-(4-fluorophenyl)propanoate;Melflufen | | CAS: | 380449-51-4 | | MF: | C24H30Cl2FN3O3 | | MW: | 498.42 | | EINECS: | | | Product Categories: | | | Mol File: | 380449-51-4.mol |  |
| | Melphalan Flufenamide Chemical Properties |
| Melting point | 138-141 °C | | Boiling point | 668.0±55.0 °C(Predicted) | | density | 1.265±0.06 g/cm3(Predicted) | | pka | 13.55±0.46(Predicted) |
| | Melphalan Flufenamide Usage And Synthesis |
| Uses | Melflufen used in the treatment or prophylaxis of osteosarcoma. | | in vivo | Melflufen (Melphalan flufenamide) (3 mg/kg; i.v.; twice-weekly for two weeks) shows anti-MM activity in xenograft mouse model[1]. | Animal Model: | CB-17 SCID mice (human plasmacytoma MM.1S xenograft mouse model)[1] | | Dosage: | 3 mg/kg | | Administration: | I.v.; twice-weekly for two weeks | | Result: | Significantly inhibited MM tumor growth and prolonged survival of mice. |
|
| | Melphalan Flufenamide Preparation Products And Raw materials |
|