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T&W GROUP |
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021-61551611 13296011611 |
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contact@trustwe.com |
Uridine,4-thio-, 2',3',5'-tribenzoate (6CI,7CI,8CI,9CI) manufacturers
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| | Uridine,4-thio-, 2',3',5'-tribenzoate (6CI,7CI,8CI,9CI) Basic information |
| Product Name: | Uridine,4-thio-, 2',3',5'-tribenzoate (6CI,7CI,8CI,9CI) | | Synonyms: | Uridine,4-thio-, 2',3',5'-tribenzoate (6CI,7CI,8CI,9CI);2’,3’,5’-Tri-O-benzoyl-4-thiouridine;2’,3’-Bis-O-(t-butyldimethylsilyl)-N1-methylpseudouridin | | CAS: | 15049-50-0 | | MF: | C30H24N2O8S | | MW: | 572.59 | | EINECS: | | | Product Categories: | | | Mol File: | 15049-50-0.mol |  |
| | Uridine,4-thio-, 2',3',5'-tribenzoate (6CI,7CI,8CI,9CI) Chemical Properties |
| Melting point | 127-129.5 °C | | density | 1.458±0.10 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | | pka | 4.656±0.20(predicted) |
| | Uridine,4-thio-, 2',3',5'-tribenzoate (6CI,7CI,8CI,9CI) Usage And Synthesis |
| Uses | 2’,3’,5’-Tri-O-benzoyl-4-thiouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. | | References | [1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005 |
| | Uridine,4-thio-, 2',3',5'-tribenzoate (6CI,7CI,8CI,9CI) Preparation Products And Raw materials |
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