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| | Methyltetrazine-propylamine HCl salt Basic information |
| Product Name: | Methyltetrazine-propylamine HCl salt | | Synonyms: | Methyltetrazine-propylamine HCl salt;1-Propanamine, 3-[4-(6-methyl-1,2,4,5-tetrazin-3-yl)phenoxy]-;3-[4-(6-methyl-1,2,4,5-tetrazin-3-yl)phenoxy]propan-1-amine;Methyltetrazine-O-propylamine | | CAS: | 1802978-47-7 | | MF: | C12H15N5O | | MW: | 245.28 | | EINECS: | | | Product Categories: | | | Mol File: | 1802978-47-7.mol |  |
| | Methyltetrazine-propylamine HCl salt Chemical Properties |
| Boiling point | 474.6±55.0 °C(Predicted) | | density | 1.198±0.06 g/cm3(Predicted) | | pka | 9.24±0.10(Predicted) |
| | Methyltetrazine-propylamine HCl salt Usage And Synthesis |
| Description | Methyltetrazine-Propylamine is click chemistry reagent, the amine group can be attached with carboxylic acid containing molecule in the presence of reagnet such as EDC or HATU. Methyltetrazine enable fast click reaction with TCO (trans-cycloctene) | | Uses | Methyltetrazine-propylamine is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | | IC 50 | Alkyl-Chain | | References | [1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
| | Methyltetrazine-propylamine HCl salt Preparation Products And Raw materials |
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