- ICA
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- $62.00
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2026-07-14
- CAS:3374-88-7
- Purity: 99.68%
- Supply Ability: 10g
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| Product Name: | ICA | | Synonyms: | N-[4-(2-Pyridinyl)-2-thiazolyl]-2-pyridinamine;2-Pyridinamine, N-[4-(2-pyridinyl)-2-thiazolyl]-;2-Pyridinamine, N-[4-(2-pyridinyl);ICA, 10 mM in DMSO | | CAS: | 3374-88-7 | | MF: | C13H10N4S | | MW: | 254.31 | | EINECS: | | | Product Categories: | | | Mol File: | 3374-88-7.mol |  |
| Boiling point | 466.4±48.0 °C(Predicted) | | density | 1.339±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMSO : ≥ 49.5 mg/mL (194.64 mM) | | pka | 3.20±0.10(Predicted) | | form | Solid | | color | Light brown to brown |
| Uses | ICA (N-(pyridin-2-yl)-4-(pyridin-2-yl)thiazol-2-amine) is a SK channel inhibitor that has antileishmanial activity with an IC50 of 2.1 μM. | | References | [1] Bhuniya D, et al. Aminothiazoles: Hit to lead development to identify antileishmanial agents. Eur J Med Chem. 2015 Sep 18;102:582-93. DOI:10.1016/j.ejmech.2015.08.013
[2] Skibsbye L, et al. Antiarrhythmic Mechanisms of SK Channel Inhibition in the Rat Atrium. J Cardiovasc Pharmacol. 2015 Aug;66(2):165-76. DOI:10.1097/FJC.0000000000000259 |
| | ICA Preparation Products And Raw materials |
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