LEIUROTOXIN I manufacturers
- LEIUROTOXIN I
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- $7.00
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2020-02-14
- CAS: 142948-19-4
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 100kg
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| | LEIUROTOXIN I Basic information |
| Product Name: | LEIUROTOXIN I | | Synonyms: | LEIUROTOXIN I;LEIUROTOXIN I (SCORPION, LEIURUS QUINQUESTRIATUS HEBRAEUS);LETX I;LETX I SCORPION TOXIN;H-ALA-PHE-CYS-ASN-LEU-ARG-MET-CYS-GLN-LEU-SER-CYS-ARG-SER-LEU-GLY-LEU-LEU-GLY-LYS-CYS-ILE-GLY-ASP-LYS-CYS-GLU-CYS-VAL-LYS-HIS-NH2;H-ALA-PHE-CYS-ASN-LEU-ARG-MET-CYS-GLN-LEU-SER-CYS-ARG-SER-LEU-GLY-LEU-LEU-GLY-LYS-CYS-ILE-GLY-ASP-LYS-CYS-GLU-CYS-VAL-LYS-HIS-NH2, (DISULFIDE BONDS BETWEEN CYS3 AND CYS21/CYS8 AND CYS26/ CYS12 AND CYS28);ALA-PHE-CYS-ASN-LEU-ARG-MET-CYS-GLN-LEU-SER-CYS-ARG-SER-LEU-GLY-LEU-LEU-GLY-LYS-CYS-ILE-GLY-ASP-LYS-CYS-GLU-CYS-VAL-LYS-HIS-NH2;SCYLLATOXIN (SCORPION, LEIURUS QUINQUESTRIATUS HEBRAEUS) | | CAS: | 142948-19-4 | | MF: | C142H237N45O39S7 | | MW: | 3423.13 | | EINECS: | | | Product Categories: | | | Mol File: | 142948-19-4.mol |  |
| | LEIUROTOXIN I Chemical Properties |
| density | 1.51±0.1 g/cm3(Predicted) |
| | LEIUROTOXIN I Usage And Synthesis |
| Uses | Scyllatoxin (Leiurotoxin I) is a peptide toxin, it can be isolated from the venom of the scorpion (Leiurus quinquestriatus hebraeus). Scyllatoxin is a blocker of small-conductance KCa (SK) channel. Scyllatoxin enhances both norepinephrine (NE) and epinephrine (Epi) release in vivo[1]. | | in vivo | Scyllatoxin (2 μM) increases basal Epi release, the nerve stimulation-induced Epi release and the exogenous acetylcholine (Ach)-induced catecholamine release by microdialysis technique to the left adrenal medulla of anesthetized adult male Wistar rats[2]. | | References | [1] Auguste P, et al. Scyllatoxin, a blocker of Ca(2+)-activated K+ channels: structure-function relationships and brain localization of the binding sites. Biochemistry. 1992 Jan 28;31(3):648-54. DOI:10.1021/bi00118a003
[2] Akiyama T, et al. Role of Ca2+-activated K+ channels in catecholamine release from in vivo rat adrenal medulla. Neurochem Int. 2010 Jan;56(2):263-9. DOI:10.1016/j.neuint.2009.10.010 |
| | LEIUROTOXIN I Preparation Products And Raw materials |
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