| Company Name: |
Sigma-Aldrich |
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021-61415566 800-8193336 |
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orderCN@merckgroup.com |
| Company Name: |
Biolab Reagents |
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027-65279366 18108604356 |
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products@biolabreagent.com |
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| | HUMAN HB-EGF Basic information |
| Product Name: | HUMAN HB-EGF | | Synonyms: | ANTI-HBEGF (CENTER) antibody produced in rabbit;HUMAN HEPARIN-BINDING EGF-LIKE GROWTH FACTOR;HUMAN DT-R;HEPARIN BINDING EPIDERMAL GROWTH FACTOR, HUMAN;HUMAN DIPHTERIA TOXIN RECEPTOR;HEPARIN-BINDING EPIDERMAL GROWTH FACTOR-LIKE GROWTH FACTOR;HEPARIN-BINDING EGF-LIKE GROWTH FACTOR;HB-EGF | | CAS: | | | MF: | | | MW: | 0 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File | ![HUMAN HB-EGF Structure]() |
| | HUMAN HB-EGF Chemical Properties |
| storage temp. | −20°C | | form | lyophilized powder | | biological source | human |
| WGK Germany | 3 | | Storage Class | 11 - Combustible Solids |
| | HUMAN HB-EGF Usage And Synthesis |
| Biochem/physiol Actions | Heparin-binding epidermal growth factor (HB-EGF), like BTC, is a heparin-binding EGF family member. Natural soluble HB-EGF is a 19 kDa glycoprotein of multiple forms due to heterogeneous truncations. Soluble HB-EGF is mitogenic and chemotactic for fibroblasts, keratinocytes, and smooth muscle cells but not capillary endothelial cells. Production of HB-EGF is detected in monocytes, macrophages, and vascular and aortic smooth muscle cells (SMC). HB-EGF may play a role in the pathogenesis of atherosclerosis. It may also be an effector of Jun-induced oncogenic transformation. HB-EGF binds to EGFR with high affinity and to ErbB with moderate affinity. |
| | HUMAN HB-EGF Preparation Products And Raw materials |
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