- Tetrahydroalstonine
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2023-02-24
- CAS:6474-90-4
- Min. Order: 5mg
- Purity: ≥98%(HPLC)
- Supply Ability: 10 g
- TETRAHYDROALSTONINE
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- $1.00
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2019-07-06
- CAS: 6474-90-4
- Min. Order: 1g
- Purity: 99%
- Supply Ability: 100KG
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| | TETRAHYDROALSTONINE Basic information |
| Product Name: | TETRAHYDROALSTONINE | | Synonyms: | 20-alpha)-lph;3,4,5,6-tetrahydro-alstonin;TETRAHYDROALSTONINE;methyl (19alpha,20alpha)-16,17-didehydro-19-methyloxayohimban-16-carboxylate;TETRAHYDROALSTONINE(RG);(20α)-16,17-Didehydro-19α-methyl-18-oxayohimban-16-carboxylic acid methyl ester;3α,4,5,6-Tetrahydroalstonine;Tetrahydroalstonine, 98%, from Schefflera octophylla (Lour.) Harms | | CAS: | 6474-90-4 | | MF: | C21H24N2O3 | | MW: | 352.43 | | EINECS: | 229-331-0 | | Product Categories: | Alkaloids;Miscellaneous Natural Products | | Mol File: | 6474-90-4.mol |  |
| | TETRAHYDROALSTONINE Chemical Properties |
| Melting point | 227°C | | Boiling point | 524.0±50.0 °C(Predicted) | | density | 1.30±0.1 g/cm3(Predicted) | | storage temp. | 4°C, protect from light | | solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | | form | Solid | | pka | 18.03±0.60(Predicted) | | color | Off-white to light yellow | | LogP | 2.880 (est) |
| | TETRAHYDROALSTONINE Usage And Synthesis |
| Uses | Tetrahydroalstonine, a indole alkaloid isolated from the fruits of Rhazya stricta, is a selective alpha 2-adrenoceptor antagonist[1][2]. | | Definition | ChEBI: Tetrahydroalstonine is a heteropentacyclic compound that is (20alpha)-16,17-didehydro-18-oxayohimban which is substituted at position 16 by a methoxycarbonyl group and at position 19 by a methyl group. It is a metabolite found in several plant species. It has a role as a plant metabolite. It is a yohimban alkaloid, an organic heteropentacyclic compound and a methyl ester. It is a conjugate base of a tetrahydroalstonine(1+). | | target | Adrenergic Receptor | | References | [1] Malik S, et al. Tetrahydroalstoninefrom Fruits of Rhazya stricta. Planta Med.1984 Jun;50(3):283. DOI:10.1055/s-2007-969707
[2] Roquebert J, et al. Inhibition of the alpha 1 and alpha 2-adrenoceptor-mediated pressor response in pithed rats by raubasine, tetrahydroalstonine and akuammigine. Eur J Pharmacol. 1984 Oct 30;106(1):203-5.https://www.ncbi.nlm.nih.gov/pubmed/6099269 DOI:10.1016/0014-2999(84)90698-8 |
| | TETRAHYDROALSTONINE Preparation Products And Raw materials |
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