ethyl 2-amino-7-hydroxy-4-(4-nitrophenyl)-4H-chromene-3-carboxylate

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ethyl 2-amino-7-hydroxy-4-(4-nitrophenyl)-4H-chromene-3-carboxylate manufacturers

ethyl 2-amino-7-hydroxy-4-(4-nitrophenyl)-4H-chromene-3-carboxylate Basic information
Product Name:ethyl 2-amino-7-hydroxy-4-(4-nitrophenyl)-4H-chromene-3-carboxylate
Synonyms:ethyl 2-amino-7-hydroxy-4-(4-nitrophenyl)-4H-chromene-3-carboxylate;4H-1-Benzopyran-3-carboxylic acid, 2-amino-7-hydroxy-4-(4-nitrophenyl)-, ethyl ester;WAY-300916;Aminopeptidase-IN-1
CAS:374102-08-6
MF:C18H16N2O6
MW:356.33
EINECS:
Product Categories:
Mol File:374102-08-6.mol
ethyl 2-amino-7-hydroxy-4-(4-nitrophenyl)-4H-chromene-3-carboxylate Structure
ethyl 2-amino-7-hydroxy-4-(4-nitrophenyl)-4H-chromene-3-carboxylate Chemical Properties
storage temp. 4°C, protect from light
form Solid
color Light yellow to yellow
Safety Information
MSDS Information
ethyl 2-amino-7-hydroxy-4-(4-nitrophenyl)-4H-chromene-3-carboxylate Usage And Synthesis
UsesAminopeptidase-IN-1 (compound 16o) is a potent insulin-regulated aminopeptidase (IRAP) inhibitor with an Ki value of 7.7 μM. Aminopeptidase-IN-1 can be used tor research cognitive and memory impairments[1].
References[1] Mountford SJ, et al. Synthesis, structure-activity relationships and brain uptake of a novel series of benzopyran inhibitors of insulin-regulated aminopeptidase. J Med Chem. 2014 Feb 27;57(4):1368-77. DOI:10.1021/jm401540f
ethyl 2-amino-7-hydroxy-4-(4-nitrophenyl)-4H-chromene-3-carboxylate Preparation Products And Raw materials
Tag:ethyl 2-amino-7-hydroxy-4-(4-nitrophenyl)-4H-chromene-3-carboxylate(374102-08-6) Related Product Information
ethyl 2-amino-4-(1-cyano-2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate ethyl 2-amino-4-(cyano-ethoxycarbonyl-methyl)-4H-chromene-3-carboxylate ethyl 2-amino-7-hydroxy-4-(4-nitrophenyl)-4H-chromene-3-carboxylate 3-Amino-1-(4-methoxy-phenyl)-1H-benzo[f]chromene-2-carboxylic acid ethyl ester Tosedostat AGM-1470