MIK665

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MIK665 Suppliers list
Company Name: SuZhou GoodChemTech Co., Ltd  Gold
Tel: 18136139868; 18136139868
Email: jinlun@goodchemtech.cn
Company Name: Elucigen bio  Gold
Tel: 13501719342 13501719342
Email: wayne.zheng@elucigenbio.com
Company Name: BOC Sciences  
Tel: 1-631-485-4226; 16314854226
Email: info@bocsci.com
Company Name: ShangHai Caerulum Pharma Discovery Co., Ltd.  
Tel: 18149758185 18149758185
Email: sales-cpd@caerulumpharma.com
Company Name: Bide Pharmatech Ltd.  
Tel: 400-164-7117 18317119277
Email: product02@bidepharm.com

MIK665 manufacturers

  • MIK665
  • MIK665 pictures
  • $135.00
  • 2026-07-14
  • CAS:1799631-75-6
  • Purity: 95.47%
  • Supply Ability: 10g
  • MIK665
  • MIK665 pictures
  • $135.00
  • 2026-07-14
  • CAS:1799631-75-6
  • Purity: 95.47%
  • Supply Ability: 10g
MIK665 Basic information
Product Name:MIK665
Synonyms:MIK665;MIK665,S64315;S64315 (MIK665);(2S)-2-(5-(3-chloro-2-methyl-4-(2-(4-methylpiperazin-1-yl)ethoxy)phenyl)-6-(4-fluorophenyl)thieno[2,3-d]pyrimidin-4-yloxy)-3-(2-((2-(2-methoxyphenyl)pyrimidin-4-yl)methoxy)phenyl)propanoic acid;MIK665 (S-64315, MIK-665);Benzenepropanoic acid, α-[[(5S)-5-[3-chloro-2-methyl-4-[2-(4-methyl-1-piperazinyl)ethoxy]phenyl]-6-(4-fluorophenyl)thieno[2,3-d]pyrimidin-4-yl]oxy]-2-[[2-(2-methoxyphenyl)-4-pyrimidinyl]methoxy]-, (αR)-;(5S)-(R)-2-((5-(3-Chloro-2-methyl-4-(2-(4-methylpiperazin-1-yl)ethoxy)phenyl)-6-(4-fluorophenyl)thieno[2,3-d]pyrimidin-4-yl)oxy)-3-(2-((2-(2-methoxyphenyl)pyrimidin-4-yl)methoxy)phenyl)propanoic acid;S64315(MIK665 ，S-64315)
CAS:1799631-75-6
MF:C47H44ClFN6O6S
MW:875.41
EINECS:
Product Categories:
Mol File:1799631-75-6.mol
MIK665 Structure
MIK665 Chemical Properties
Boiling point 909.4±65.0 °C(Predicted)
density 1.324±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMSO: soluble
form A solid
pka2.53±0.11(Predicted)
color White to off-white
InChIKeyPKYIMGFMRFVOMB-UHFFFAOYSA-N
SMILESO(C1N=CN=C2SC(C3C=CC(F)=CC=3)=C(C3C=CC(OCCN4CCN(C)CC4)=C(Cl)C=3C)C=12)C(C(=O)O)CC1C=CC=CC=1OCC1C=CN=C(C2C=CC=CC=2OC)N=1
Safety Information
MSDS Information
MIK665 Usage And Synthesis
UsesMIK665 (S-64315), derived from S63845, is a myeloid cell leukemia sequence 1 (MCL1) inhibitor[1]. MIK665 has an IC50 of 1.81 nM for MCL1[2].
IC 50Mcl-1: 1.81 nM (IC50)
References[1] Mukherjee N, et al. Simultaneously Inhibiting BCL2 and MCL1 Is a Therapeutic Option for Patients with Advanced Melanoma. Cancers (Basel). 2020;12(8):2182. Published 2020 Aug 5. DOI:10.3390/cancers12082182
[2] Zoltán SZLáVIK, et al. New hydroxyester derivatives, a process for their preparation and pharmaceutical compositions containing them. WO2016207225A1.
MIK665 Preparation Products And Raw materials
Tag:MIK665(1799631-75-6) Related Product Information
(R)-MIK665 ABBV-467 MIK665 Ethyl (αR)-α-[[(5S)-5-[3-chloro-2-methyl-4-[2-(1-piperazinyl)ethoxy]phenyl]-6-(4-fluorophenyl)thieno[2,3-d]pyrimidin-4-yl]oxy]-2-[[2-(2-methoxyphenyl)-4-pyrimidinyl]methoxy]benzenepropanoate GDLMLQJISATCEL-UHFFFAOYSA-M 2,6-dibromo-4-[1-(3-bromo-4-hydroxyphenyl)-1-methylethyl]phenol