- L-Selenocystine
-
- $54.00 / 100mg
-
2026-01-26
- CAS:29621-88-3
- Min. Order:
- Purity: 99.36%
- Supply Ability: 10g
- selenocystine
-
- $1.00 / 1g
-
2025-02-13
- CAS:29621-88-3
- Min. Order: 1g
- Purity: 98%
- Supply Ability: 1000
- L-SELENOCYSTINE
-
- $1.00 / 1KG
-
2020-03-06
- CAS:29621-88-3
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 200kg
|
| | L-SELENOCYSTINE Basic information |
| Product Name: | L-SELENOCYSTINE | | Synonyms: | SELENO-L-CYSTINE;(R,R)-3,3'-DISELENO-BIS(2-AMINOPROPIONIC ACID);L-SELENOCYSTINE;3’-diselenodi-l-alanin;l-3,3’-diselenodialanine;3,3'-DISELENO-L-ALANINE;L-SELENOCYSTINE 98%;(R,R)-3,3μ-Diseleno-bis(2-aminopropionic acid), L-Selenocystine | | CAS: | 29621-88-3 | | MF: | C6H12N2O4Se2 | | MW: | 334.09 | | EINECS: | 608-382-6 | | Product Categories: | amino acids | | Mol File: | 29621-88-3.mol |  |
| | L-SELENOCYSTINE Chemical Properties |
| Melting point | 224.5-229.5 °C (lit.) | | Boiling point | 538.3±60.0 °C(Predicted) | | storage temp. | 2-8°C | | solubility | Aqueous Acid (Slightly), Aqueous Base (Slightly) | | pka | 1.69±0.10(Predicted) | | form | Powder | | color | Yellow | | Optical Rotation | [α]20/D 28°, c = 1 in NaOH | | BRN | 1969559 | | Stability: | Hygroscopic | | Major Application | peptide synthesis | | InChI | 1S/C6H12N2O4Se2/c7-3(5(9)10)1-13-14-2-4(8)6(11)12/h3-4H,1-2,7-8H2,(H,9,10)(H,11,12)/t3-,4-/m0/s1 | | InChIKey | JULROCUWKLNBSN-IMJSIDKUSA-N | | SMILES | N[C@@H](C[Se][Se]C[C@H](N)C(O)=O)C(O)=O |
| Hazard Codes | T,N | | Risk Statements | 23/25-33-50/53 | | Safety Statements | 20/21-28-45-60-61 | | RIDADR | UN 3283 6.1/PG 3 | | WGK Germany | 3 | | RTECS | AY6032000 | | HazardClass | 6.1 | | PackingGroup | III | | HS Code | 29319090 | | Storage Class | 6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects | | Hazard Classifications | Acute Tox. 3 Inhalation
Acute Tox. 3 Oral
Aquatic Acute 1
Aquatic Chronic 1
STOT RE 2 |
| Provider | Language |
|
ACROS
| English |
| | L-SELENOCYSTINE Usage And Synthesis |
| Description | L-Selenocystine is a diselenide-bridged amino acid that may be confused with selenocysteine (Sec), which is a rare amino acid featuring a single selenium atom. L-Selenocystine is a redox-active selenium compound that has both anti- and pro-oxidant actions. This compound can be reduced by low molecular thiols and disulfide reductases to Sec. It is reduced to Sec by mammalian thioredoxin reductase (apparent Km = 6.0 μM), and this property can be used to assay thioredoxin reductase activity. L-Selenocystine induces an unfolded protein response, ER stress, and large cytoplasmic vacuolization in HeLa cells and has cytostatic effects in a range of cancer cell types. | | Chemical Properties | yellow fine powder | | Uses | Seleno-L-cystine can be used for the synthesis of:
- Biologically active selenol compounds.
- Non-natural selenylated diamino acids.
| | reaction suitability | reaction type: solution phase peptide synthesis | | References | [1] SPALLHOLZ J E. On the nature of selenium toxicity and carcinostatic activity[J]. Free Radical Biology and Medicine, 1994, 17 1: Pages 45-64. DOI: 10.1016/0891-5849(94)90007-8
[2] SOUGAT MISRA. Redox-active selenium compounds–from toxicity and cell death to cancer treatment.[J]. Nutrients, 2015, 7 5: 3536-3556. DOI: 10.3390/nu7053536
[3] BRIAN CUNNIFF . A direct and continuous assay for the determination of thioredoxin reductase activity in cell lysates[J]. Analytical biochemistry, 2013, 443 1: Pages 34-40. DOI: 10.1016/j.ab.2013.08.013
[4] MARITA WALLENBERG. Selenium induces a multi-targeted cell death process in addition to ROS formation[J]. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE, 2014, 18 4: 671-684. DOI: 10.1111/jcmm.12214 |
| | L-SELENOCYSTINE Preparation Products And Raw materials |
|