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22-HDHA

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Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Products Intro: Product Name:22-HDHA
CAS:90780-46-4
Package:50μg;
Company Name: Yichang Zhongyitai Trading Co., Ltd.  
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Products Intro: Product Name:22-Hydroxy-4(Z),7(Z),10(Z),13(Z),16(Z),19(Z)-Docosahexaenoic acid
CAS:90780-46-4
Purity:98+% Package:50ug
Company Name: Alfa Chemistry  
Tel: 1-516-6625404
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Products Intro: Product Name:22-hydroxy-4(Z),7(Z),10(Z),13(Z),16(Z),19(Z)-docosahexaenoic acid
CAS:90780-46-4
Purity:95%+ Package:1g;10g;100g;1KG;5KG
Company Name: Shanghai Hongye Biotechnology Co. Ltd  
Tel: 400-9205774
Email: sales@glpbio.cn
Products Intro: Product Name:22-HDHA
CAS:90780-46-4
Purity:>98% Package:1mg;10mg;50mg;100mg;
Company Name: ChemeGen(Shanghai) Biotechnology Co.,Ltd.  
Tel: 18818260767
Email: sales@chemegen.com
Products Intro: Product Name:22-HDHA
CAS:90780-46-4
Purity:98% Package:10 mg;50 mg;100 mg;500 mg;1 g;5 g;10 g

22-HDHA manufacturers

  • 22-HDHA
  • 22-HDHA pictures
  • 2025-12-22
  • CAS:90780-46-4
  • Purity:
  • Supply Ability: 10g
22-HDHA Basic information
Product Name:22-HDHA
Synonyms:22-HDHA;22-hydroxy-4(Z),7(Z),10(Z),13(Z),16(Z),19(Z)-docosahexaenoic acid;22HDHA,22 HDHA;4,7,10,13,16,19-Docosahexaenoic acid, 22-hydroxy-, (4Z,7Z,10Z,13Z,16Z,19Z)-;22-Hydroxy-4(Z),7(Z),10(Z),13(Z),16(Z),19(Z)-DHA
CAS:90780-46-4
MF:C22H32O3
MW:344.49
EINECS:
Product Categories:
Mol File:90780-46-4.mol
22-HDHA Structure
22-HDHA Chemical Properties
Boiling point 503.6±38.0 °C(Predicted)
density 0.997±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility 0.1 M Na2CO3: 2 mg/ml; DMF: Miscible; DMSO: Miscible; Ethanol: Miscible; PBS (pH 7.2): 0.8 mg/ml
pka4.58±0.10(Predicted)
Safety Information
MSDS Information
22-HDHA Usage And Synthesis
Description22-HDHA is an oxidation product of docosahexaenoic acid (DHA; ).1 In vitro, it is formed upon incubation of rat liver microsomes with DHA and NADPH and also by the human cytochrome P450 (CYP) isoform CYP4F3B in BTI-TN-5B1-4 microsomes.1,2 Serum levels of 22-HDHA increase following dietary DHA supplementation in humans.3
Uses22-HDHA (22-Hydroxy Docosahexaenoic acid) is an oxidation product of docosahexaenoic acid. In vitro, it is formed upon incubation of rat liver microsomes with DHA and NADPH and also by the human cytochrome P450 (CYP) isoform CYP4F3B in BTI-TN-5B1-4 microsomes. Serum levels of 22-HDHA increase following dietary DHA supplementation in humans.
DefinitionChEBI: (4Z,7Z,10Z,13Z,16Z,19Z)-22-hydroxydocosahexaenoic acid is a HDoHE obtained by hydroxylation at position 2 of all-cis-docosa-4,7,10,13,16,19-hexaenoic acid. It is a hydroxydocosahexaenoic acid and a homoallylic alcohol. It is functionally related to an all-cis-docosa-4,7,10,13,16,19-hexaenoic acid. It is a conjugate acid of a (4Z,7Z,10Z,13Z,16Z,19Z)-22-hydroxydocosahexaenoate.
References1. VanRollins, M., Baker, R.C., Sprecher, H., et al. Oxidation of docosahexaenoic acid by rat liver microsomes J. Biol. Chem. 259(9),5776-5783(1984).
2. Harmon, S.D., Fang, X., Kaduce, T.L., et al. Oxygenation of ω-3 fatty acids by human cytochrome P450 4F3B: Effect on 20-hydroxyeicosatetraenoic acid production Prostaglandins Leukot. Essent. Fatty Acids 75(3),169-177(2006).
3. Fischer, R., Konkel, A., Mehling, H., et al. Dietary omega-3 fatty acids modulate the eicosanoid profile in man primarily via the CYP-epoxygenase pathway J. Lipid Res. 55(6),1150-1164(2014).
22-HDHA Preparation Products And Raw materials
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