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| | Clomipramine-d3 Basic information |
| Product Name: | Clomipramine-d3 | | Synonyms: | 5H-Dibenzb,fazepine-5-propanamine, 3-chloro-10,11-dihydro-N-methyl-N-(methyl-d3)-;CLOMIPRAMINE-D3,100/MLINMETHANOL;[2H3]-Clomipramine HCl;[2H3]-Clomipramine;Clomipramine-d3 | | CAS: | 136765-29-2 | | MF: | C18H19ClD3N3 | | MW: | 318.86 | | EINECS: | 604-604-1 | | Product Categories: | | | Mol File: | 136765-29-2.mol |  |
| | Clomipramine-d3 Chemical Properties |
| storage temp. | Store at -20°C | | solubility | Soluble in DMSO |
| | Clomipramine-d3 Usage And Synthesis |
| Uses | Clomipramine-d3 is the deuterium labeled Clomipramine. Clomipramine is a serotonin transporter (SERT), norepinephrine transporter (NET) dopamine transporter (DAT) blocker with Ki of 0.14, 54 and 3 nM, respectively[1][2]. | | References | [1] McTavish, D. and P. Benfield, Clomipramine. An overview of its pharmacological properties and a review of its therapeutic use in obsessive compulsive disorder and panic disorder. Drugs, 1990. 39(1): p. 136-53. DOI:10.2165/00003495-199039010-00010
[2] Owens, M.J., et al., Neurotransmitter receptor and transporter binding profile of antidepressants and their metabolites. J Pharmacol Exp Ther, 1997. 283(3): p. 1305-22. PMID:9400006 |
| | Clomipramine-d3 Preparation Products And Raw materials |
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