BMS-199264 HYDROCHLORIDE

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BMS-199264 HYDROCHLORIDE manufacturers
BMS-199264 HYDROCHLORIDE Basic information
Product Name:BMS-199264 HYDROCHLORIDE
Synonyms:BMS-199264 HYDROCHLORIDE;BMS-199264 hydrochloride >=98% (HPLC);BMS199264 hydrochloride,BMS 199264 hydrochloride
CAS:186180-83-6
MF:C26H32Cl2N4O4S
MW:567.53
EINECS:
Product Categories:
Mol File:186180-83-6.mol
BMS-199264 HYDROCHLORIDE Structure
BMS-199264 HYDROCHLORIDE Chemical Properties
storage temp. room temp
form powder
color white to beige
Safety Information
MSDS Information
BMS-199264 HYDROCHLORIDE Usage And Synthesis
UsesBMS-199264 hydrochloride is an inhibitor of F1F0 ATP hydrolase (IC50=0.5 μM) without inhibitory effect on F1F0 ATP synthase. BMS-199264 hydrochloride selectively inhibits ATP decline during ischemia to reduces cardiac necrosis. BMS-199264 hydrochloride also enhances the recovery of contractile function following reperfusion[1].
References[1] Grover GJ, et al. Pharmacological profile of the selective mitochondrial F1F0 ATP hydrolase inhibitor BMS-199264 in myocardial ischemia. Cardiovasc Ther. 2008 Winter;26(4):287-96. DOI:10.1111/j.1755-5922.2008.00065.x
BMS-199264 HYDROCHLORIDE Preparation Products And Raw materials
Tag:BMS-199264 HYDROCHLORIDE(186180-83-6) Related Product Information
2H-1-Benzopyran-3-ol, 4-[(4-chlorophenyl)(1H-imidazol-2-ylmethyl)amino]-3,4-dihydro-2,2-dimethyl-6-(1-piperidinylsulfonyl)-, (3S,4R)- BMS-199264 HYDROCHLORIDE Parimifasor Cyclocreatine D-2-Hydroxypentanedioic acid disodium salt Ammonium formate