N-(4-chlorophenyl)-4-hydroxy-3-(4-(4-(trifluoromethoxy)phenyl)piperazin-1-yl)butanamide

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N-(4-chlorophenyl)-4-hydroxy-3-(4-(4-(trifluoromethoxy)phenyl)piperazin-1-yl)butanamide Suppliers list
Company Name: InvivoChem  Gold
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Company Name: Zhengzhou Haode Pharmaceutical Technology Co.,Ltd  Gold
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Company Name: ShangHai Caerulum Pharma Discovery Co., Ltd.  
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Company Name: Shanghai Macklin Biochemical Co.,Ltd.  
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Company Name: Shanghai Beckham Medical Technology Co., Ltd  
Tel: 13816613772
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N-(4-chlorophenyl)-4-hydroxy-3-(4-(4-(trifluoromethoxy)phenyl)piperazin-1-yl)butanamide manufacturers

  • VBIT-4
  • VBIT-4 pictures
  • $68.00
  • 2026-07-27
  • CAS:2086257-77-2
  • Purity: 99.97%
  • Supply Ability: 10g
  • VBIT-4
  • VBIT-4 pictures
  • $68.00
  • 2026-07-27
  • CAS:2086257-77-2
  • Purity: 99.97%
  • Supply Ability: 10g
N-(4-chlorophenyl)-4-hydroxy-3-(4-(4-(trifluoromethoxy)phenyl)piperazin-1-yl)butanamide Basic information
Product Name:N-(4-chlorophenyl)-4-hydroxy-3-(4-(4-(trifluoromethoxy)phenyl)piperazin-1-yl)butanamide
Synonyms:N-(4-chlorophenyl)-4-hydroxy-3-(4-(4-(trifluoromethoxy)phenyl)piperazin-1-yl)butanamide;VBIT4,VBIT 4;VBIT-4, 10 mM in DMSO;N-(4-chlorophenyl)-4-hydroxy-3-(4-(4-(trifluoromethoxy)phenyl)azine-1-yl)butylamide;VBIT-4
CAS:2086257-77-2
MF:C21H23ClF3N3O3
MW:457.8738296
EINECS:829-870-7
Product Categories:
Mol File:2086257-77-2.mol
N-(4-chlorophenyl)-4-hydroxy-3-(4-(4-(trifluoromethoxy)phenyl)piperazin-1-yl)butanamide Structure
N-(4-chlorophenyl)-4-hydroxy-3-(4-(4-(trifluoromethoxy)phenyl)piperazin-1-yl)butanamide Chemical Properties
form Solid
color Light yellow to yellow
InChIInChI=1S/C21H23ClF3N3O3/c22-15-1-3-16(4-2-15)26-20(30)13-18(14-29)28-11-9-27(10-12-28)17-5-7-19(8-6-17)31-21(23,24)25/h1-8,18,29H,9-14H2,(H,26,30)
InChIKeyQYSQXVAEFPWMEM-UHFFFAOYSA-N
SMILESC(NC1=CC=C(Cl)C=C1)(=O)CC(N1CCN(C2=CC=C(OC(F)(F)F)C=C2)CC1)CO
Safety Information
MSDS Information
N-(4-chlorophenyl)-4-hydroxy-3-(4-(4-(trifluoromethoxy)phenyl)piperazin-1-yl)butanamide Usage And Synthesis
DescriptionThis product was discontinued for commercial reason.
UsesVBIT-4 is an inhibitor of voltage-dependent anion channel 1 (VDAC1) oligomerization with a binding affinity (Kd) of 17 μM. VBIT-4, as an apoptosis inhibitor, can be used for therapeutic purposes in apoptosis-associated disorders, such as neurodegenerative and cardiovascular diseases[1].
References[1] Ben-Hail D, et al. Novel Compounds Targeting the Mitochondrial Protein VDAC1 Inhibit Apoptosis and Protect against Mitochondrial Dysfunction. J Biol Chem. 2016 Nov 25;291(48):24986-25003. DOI:10.1074/jbc.M116.744284
N-(4-chlorophenyl)-4-hydroxy-3-(4-(4-(trifluoromethoxy)phenyl)piperazin-1-yl)butanamide Preparation Products And Raw materials
Tag:N-(4-chlorophenyl)-4-hydroxy-3-(4-(4-(trifluoromethoxy)phenyl)piperazin-1-yl)butanamide(2086257-77-2) Related Product Information
6H-Benzofuro[3a,3,2-ef][2]benzazepin-6-ol, 4a,5,9,10,11,12-hexahydro-3-methoxy-11-methyl-, 6-benzoate DIDS NA 1,3-Bis(4-aminophenyl)urea Ion Channel Compound Library VBIT-12