ALLO-2
(Smo inhibitor ALLO-2) manufacturers
- ALLO-2
-
- $58.00
-
2026-07-27
- CAS:1357350-60-7
- Purity: 99.19%
- Supply Ability: 10g
- ALLO-2
-
- $58.00
-
2026-07-27
- CAS:1357350-60-7
- Purity: 99.19%
- Supply Ability: 10g
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| | ALLO-2
(Smo inhibitor ALLO-2) Basic information |
| Product Name: | ALLO-2
(Smo inhibitor ALLO-2) | | Synonyms: | ALLO-2
(Smo inhibitor ALLO-2);ALLO-2;1H-Indazol-5-amine, N-[4-[4-(trifluoromethoxy)phenyl]-2-pyrimidinyl]-;N-(4-(4-(Trifluoromethoxy)phenyl)pyrimidin-2-yl)-1H-indazol-5-amine;Inhibitor,ALLO-2,inhibit,Smo,ALLO 2,Smoothened,ALLO2;ALLO-2, 10 mM in DMSO | | CAS: | 1357350-60-7 | | MF: | C18H12F3N5O | | MW: | 371.32 | | EINECS: | | | Product Categories: | | | Mol File: | 1357350-60-7.mol |  |
| | ALLO-2
(Smo inhibitor ALLO-2) Chemical Properties |
| storage temp. | Store at -20°C | | solubility | DMSO : 125 mg/mL (336.64 mM) | | form | Solid | | color | Light yellow to yellow |
| | ALLO-2
(Smo inhibitor ALLO-2) Usage And Synthesis |
| Uses | ALLO-2 is a potent drug-resistant Smoothened (Smo) mutant antagonist that inhibits Smo agonist Hh-Ag1.5-induced luciferase expression in TM3-Gli-Luc cells with IC50 of 6 nM[1]. | | References | [1] Tao H, et al. Small molecule antagonists in distinct binding modes inhibit drug-resistant mutant of smoothened. Chem Biol. 2011 Apr 22;18(4):432-7. DOI:10.1016/j.chembiol.2011.01.018 |
| | ALLO-2
(Smo inhibitor ALLO-2) Preparation Products And Raw materials |
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