2-[4-(6-Benzyl-4,5-dimethylpyridazin-3-yl)-2-methyl-3,4,5,6-tetrahydro-2H-[1,2]bipyrazinyl-5-yl]-propan-2-ol

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2-[4-(6-Benzyl-4,5-dimethylpyridazin-3-yl)-2-methyl-3,4,5,6-tetrahydro-2H-[1,2]bipyrazinyl-5-yl]-propan-2-ol Suppliers list
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2-[4-(6-Benzyl-4,5-dimethylpyridazin-3-yl)-2-methyl-3,4,5,6-tetrahydro-2H-[1,2]bipyrazinyl-5-yl]-propan-2-ol manufacturers

  • LEQ506
  • LEQ506 pictures
  • $58.00
  • 2026-07-27
  • CAS:1204975-42-7
  • Purity: 99.76%
  • Supply Ability: 10g
  • LEQ506
  • LEQ506 pictures
  • $58.00
  • 2026-07-27
  • CAS:1204975-42-7
  • Purity: 99.76%
  • Supply Ability: 10g
2-[4-(6-Benzyl-4,5-dimethylpyridazin-3-yl)-2-methyl-3,4,5,6-tetrahydro-2H-[1,2]bipyrazinyl-5-yl]-propan-2-ol Basic information
Product Name:2-[4-(6-Benzyl-4,5-dimethylpyridazin-3-yl)-2-methyl-3,4,5,6-tetrahydro-2H-[1,2]bipyrazinyl-5-yl]-propan-2-ol
Synonyms:2-[4-(6-Benzyl-4,5-dimethylpyridazin-3-yl)-2-methyl-3,4,5,6-tetrahydro-2H-[1,2]bipyrazinyl-5-yl]-propan-2-ol;2-[(R)-4-(6-benzyl-4,5-dimethyl-pyridazin-3-yl)-2-methyl-3,4,5,6-tetrahydro-2H-[1,2']bipyrazinyl-5'-yl]-propan-2-ol;NVP-LEQ506;LEQ-506;(R)-2-(5-(4-(6-Benzyl-4,5-dimethylpyridazin-3-yl)-2-methylpiperazin-1-yl)pyrazin-2-yl)propan-2-ol;2-Pyrazinemethanol, 5-[(2R)-4-[4,5-dimethyl-6-(phenylmethyl)-3-pyridazinyl]-2-methyl-1-piperazinyl]-α,α-dimethyl-;LEQ-506,Inhibitor,LEQ 506,Smo,LEQ506,Smoothened,inhibit;LEQ506, 10 mM in DMSO
CAS:1204975-42-7
MF:C25H32N6O
MW:432.56
EINECS:
Product Categories:
Mol File:1204975-42-7.mol
2-[4-(6-Benzyl-4,5-dimethylpyridazin-3-yl)-2-methyl-3,4,5,6-tetrahydro-2H-[1,2]bipyrazinyl-5-yl]-propan-2-ol Structure
2-[4-(6-Benzyl-4,5-dimethylpyridazin-3-yl)-2-methyl-3,4,5,6-tetrahydro-2H-[1,2]bipyrazinyl-5-yl]-propan-2-ol Chemical Properties
Melting point 132 °C
Boiling point 685.4±55.0 °C(Predicted)
density 1.170±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMSO : ≥ 100 mg/mL (231.18 mM)
pka12.84±0.29(Predicted)
form Solid
color White to yellow
Safety Information
MSDS Information
2-[4-(6-Benzyl-4,5-dimethylpyridazin-3-yl)-2-methyl-3,4,5,6-tetrahydro-2H-[1,2]bipyrazinyl-5-yl]-propan-2-ol Usage And Synthesis
UsesLEQ506, is a second-generation inhibitor of smoothened (Smo) with IC50s of 2 and 4 nM in human and mouse, respectively.
2-[4-(6-Benzyl-4,5-dimethylpyridazin-3-yl)-2-methyl-3,4,5,6-tetrahydro-2H-[1,2]bipyrazinyl-5-yl]-propan-2-ol Preparation Products And Raw materials
Tag:2-[4-(6-Benzyl-4,5-dimethylpyridazin-3-yl)-2-methyl-3,4,5,6-tetrahydro-2H-[1,2]bipyrazinyl-5-yl]-propan-2-ol(1204975-42-7) Related Product Information
(R)-Methyl 5-(4-(6-benzyl-4,5-dimethylpyridazin-3-yl)-2-methylpiperazin-1-yl)pyrazine-2-carboxylate 2-[4-(6-Benzyl-4,5-dimethylpyridazin-3-yl)-2-methyl-3,4,5,6-tetrahydro-2H-[1,2]bipyrazinyl-5-yl]-propan-2-ol 3-Keto-N-aminoethyl-Naminocaproyldihydrocinnamoyl Cyclopamine Anti-Aging Compound Library Anti-cancer compound library SANT-1