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| | Androsta-1,4,6-triene-3,17-dione Basic information |
| Product Name: | Androsta-1,4,6-triene-3,17-dione | | Synonyms: | Δ1,4,6-androgen;1,4,6-Andorstatriene-3,17-dione;Androsta-1,4,6-triene-3,17-dione (1.0mg/mL in MeOH);1,4,6-Androstatriene-3,17-dione(ATD);ANDROSTA-1,4,6-TRIENE-3,17-DIONE(ATD);6-triene-3;Androsta-1;Androsterol 1,4,6-triene-3,17-dione | | CAS: | 633-35-2 | | MF: | C19H22O2 | | MW: | 282.38 | | EINECS: | 1806241-263-5 | | Product Categories: | Various Metabolites and Impurities;Metabolites & Impurities;Steroids | | Mol File: | 633-35-2.mol |  |
| | Androsta-1,4,6-triene-3,17-dione Chemical Properties |
| Melting point | 164-1650C | | Boiling point | 452.8±45.0 °C(Predicted) | | density | 1.16±0.1 g/cm3(Predicted) | | storage temp. | -20°C Freezer | | solubility | methanol: 50 mg/mL, soluble | | form | powder |
| Safety Statements | 22-24/25 | | WGK Germany | 3 | | RTECS | BV8082250 |
| | Androsta-1,4,6-triene-3,17-dione Usage And Synthesis |
| Chemical Properties | Brownish Yellow Solid | | Uses | A solution of Androsta-1,4,6-triene-3,17-dione which is selective receptor modulator inhibitor. | | Definition | ChEBI: An androstanoid that is androsta-1,4,6-triene substituted by oxo groups at positions 3 and 17. | | in vivo | Androsta-1,4,6-triene-3,17-dione (25-100 mg/kg; s.c.) prevents the normal rise in ovarian estradiol concentrations[2].
Androsta-1,4,6-triene-3,17-dione may act in vivo to inhibit fertility by inhibition of estrogen biosynthesis [1].
| Animal Model: | Rats (220-250 g)[2] | | Dosage: | 25 mg/kg, 100 mg/kg | | Administration: | Subcutaneous injection | | Result: | Prevented the normal rise in ovarian estradiol concentrations with a single injection 3 hours before the time of the estrogen surge on proestrus. |
| | IC 50 | Aromatase |
| | Androsta-1,4,6-triene-3,17-dione Preparation Products And Raw materials |
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