- Cardiogenol C
-
- $38.00
-
2026-05-11
- CAS:671225-39-1
- Purity: 98.46%
- Supply Ability: 10g
|
| | CARDIOGENOL C HYDROCHLORID Basic information |
| Product Name: | CARDIOGENOL C HYDROCHLORID | | Synonyms: | CS-1613;Cardiogenol C - CAS 671225-39-1 - Calbiochem;CARDIOGENOL C HYDROCHLORID;Cardiogenol;2-(2-(4-methoxyphenylamino)pyrimidin-4-ylamino)ethanol hydrochloride;CARDIOGENOL C HCL;2-[[2-[(4-Methoxyphenyl)amino]-4-pyrimidinyl]amino]ethanol;Ethanol, 2-[[2-[(4-methoxyphenyl)amino]-4-pyrimidinyl]amino]- | | CAS: | 671225-39-1 | | MF: | C13H16N4O2 | | MW: | 260.29 | | EINECS: | | | Product Categories: | Inhibitors | | Mol File: | 671225-39-1.mol |  |
| | CARDIOGENOL C HYDROCHLORID Chemical Properties |
| Boiling point | 520.3±58.0 °C(Predicted) | | density | 1.305±0.06 g/cm3(Predicted) | | storage temp. | −20°C | | solubility | H2O: 10 mg/mL, soluble | | form | solid | | pka | 14.53±0.10(Predicted) | | color | white | | Water Solubility | H2O: soluble 10mg/mL | | InChI | 1S/C13H16N4O2.ClH/c1-19-11-4-2-10(3-5-11)16-13-15-7-6-12(17-13)14-8-9-18;/h2-7,18H,8-9H2,1H3,(H2,14,15,16,17);1H | | InChIKey | QQAHYSZVJLHCNA-UHFFFAOYSA-N | | SMILES | Cl[H].COc1ccc(Nc2nccc(NCCO)n2)cc1 |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-36 | | WGK Germany | 3 | | Storage Class | 11 - Combustible Solids |
| | CARDIOGENOL C HYDROCHLORID Usage And Synthesis |
| Uses | Cardiogenol C is a potent cell-permeable pyrimidine inducer which prompts the differentiation of ESCs into cardiomyocytes (EC50=100 nM)[1]. Cardiogenol C also acts cardiomyogenic on already lineage-committed progenitor cell types with a limited degree of plasticity. Cardiogenol C is a useful cardiomyogenic agent and can be used as a tool to improve cardiac repair by cell transplantation therapy in animal models[2]. | | Biological Activity | Induces differentiation of mouse embryonic stem cells (ESCs) into cardiomyocytes (EC 50 =100 nM). | | References | [1] Wu X, et al. Small molecules that induce cardiomyogenesis in embryonic stem cells.J Am Chem Soc.2004 Feb 18;126(6):1590-1. DOI:10.1021/ja038950i [2] Mike AK, et al. Small moleculecardiogenol Cupregulates cardiac markers and induces cardiac functional properties in lineage-committed progenitor cells. Cell Physiol Biochem.2014;33(1):205-21. DOI:10.1159/000356663 |
| | CARDIOGENOL C HYDROCHLORID Preparation Products And Raw materials |
|