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Sigma-Aldrich |
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BOC Sciences |
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Poly-L-histidine hydrochloride MW manufacturers
- Poly-L-histidine
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- $2.00
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2026-08-25
- CAS:26062-48-6
- Min. Order: 1kg
- Purity: 99%
- Supply Ability: 100kg
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| | Poly-L-histidine hydrochloride MW Basic information |
| | Poly-L-histidine hydrochloride MW Chemical Properties |
| storage temp. | -20°C | | form | powder or solid | | color | white to light yellow | | Major Application | cell analysis | | InChI | 1S/C6H9N3O2/c7-5(6(10)11)1-4-2-8-3-9-4/h2-3,5H,1,7H2,(H,8,9)(H,10,11)/t5-/m0/s1 | | InChIKey | HNDVDQJCIGZPNO-YFKPBYRVSA-N | | SMILES | [N+H3][C@@H](Cc1[nH]cnc1)C(=O)[O-] |
| WGK Germany | 3 | | Storage Class | 11 - Combustible Solids |
| | Poly-L-histidine hydrochloride MW Usage And Synthesis |
| Uses | Poly-L-histidine has been used:
- as a polycation for the dispersion of multi-wall carbon nanotubes (MWCNTs)
- as a polyionic compound to investigate its ability to rupture extracellular enveloped virus membrane
- in screening its anti-prion activity in cell based and in vivo anti-prion assay
| | Definition | ChEBI: Histidine is an alpha-amino acid that is propanoic acid bearing an amino substituent at position 2 and a 1H-imidazol-4-yl group at position 3. It has a role as a metabolite. It is an alpha-amino acid, a member of imidazoles, an aromatic amino acid and a polar amino acid. It contains a 1H-imidazol-4-ylmethyl group. It is a conjugate base of a histidinium(1+). It is a conjugate acid of a histidinate(1-). | | General Description | Poly-L-histidine is an amphoteric compound. The imidazole ring in its structure enables protonationdeprotonation. | | Biochem/physiol Actions | Poly-L-histidine (Phis) copolymers are biocompatible, pH responsive and are less toxic. It exhibits endolysosomal escape funcationality. The copolymer of Phis with poly(ethylene glycol)poly(d,l-lactide) (PEG-PLA) is effective in delivering doxorubicin. pH sensitive poly(l-histidine) copolymer micelles have application in delivering anticancer drugs in acidic microenvironment. |
| | Poly-L-histidine hydrochloride MW Preparation Products And Raw materials |
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