MMRi64 manufacturers
- MMRi64
-
- $51.00
-
2026-07-27
- CAS:430458-66-5
- Purity: 99.93%
- Supply Ability: 10g
|
| Product Name: | MMRi64 | | Synonyms: | MMRi64;8-Quinolinol, 7-[(2,3-dichlorophenyl)[(4-methyl-2-pyridinyl)amino]methyl]-;MMRi64,MMRi-64;T28078;7-((2,3-Dichlorophenyl)((4-methylpyridin-2-yl)amino)methyl)quinolin-8-ol;Samuraciclib hydrochloride dihydrate | | CAS: | 430458-66-5 | | MF: | C22H17Cl2N3O | | MW: | 410.3 | | EINECS: | | | Product Categories: | | | Mol File: | 430458-66-5.mol |  |
| | MMRi64 Chemical Properties |
| Boiling point | 595.5±45.0 °C(Predicted) | | density | 1.402±0.06 g/cm3(Predicted) | | pka | 4.01±0.50(Predicted) | | form | Solid | | color | White to off-white |
| | MMRi64 Usage And Synthesis |
| Uses | MMRi64 disrupts Mdm2-MdmX interactions. MMRi64 downregulates Mdm2 and MdmX in leukemia cells. MMRi64 induces p53 accumulation, and induces the apoptotic arm of the p53 pathway in leukemia/lymphoma cells. MMRi64 can be used for cancer research[1]. | | References | [1] Wu W, et al. Targeting RING domains of Mdm2-MdmX E3 complex activates apoptotic arm of the p53 pathway in leukemia/lymphoma cells. Cell Death Dis. 2015 Dec 31;6(12):e2035. DOI:10.1038/cddis.2015.358 |
| | MMRi64 Preparation Products And Raw materials |
|