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12(S)-Hydroxy-16-heptadecynoic acid manufacturers
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| | 12(S)-Hydroxy-16-heptadecynoic acid Basic information |
| | 12(S)-Hydroxy-16-heptadecynoic acid Chemical Properties |
| Boiling point | 432.8±20.0 °C(Predicted) | | density | 0.989±0.06 g/cm3(Predicted) | | solubility | DMF: 50 mg/ml; DMSO: 50 mg/ml; Ethanol: 50 mg/ml; PBS pH 7.2: 1 mg/ml | | form | A crystalline solid | | pka | 4.78±0.10(Predicted) |
| | 12(S)-Hydroxy-16-heptadecynoic acid Usage And Synthesis |
| Description | 12(S)-hydroxy-16-Heptadecynoic acid is a mechanism-based inhibitor of cytochrome P450 ω-hydroxylase. It inhibits prostaglandin ω-hydroxylase with a Ki value of 1.8 μM. | | Uses | 12(S)-Hydroxy-16-heptadecynoic acid ((12S)-12-Hydroxy-15-hexadecynoic acid) is a mechanism-based inhibitor of cytochrome P450 ω-hydroxylase. It inhibits prostaglandin ω-hydroxylase with a Ki value of 1.8 μM. | | Definition | ChEBI: 12S-Hydroxy-16-heptadecynoic acid is a long-chain fatty acid. | | References | [1] Burger, et al. Mechanism-based inhibitors of prostaglandin w -hydrolase: (R)- and (S)-12-hydroxy-16-heptadecynoic acid and 2,2-dimethyl-12-hydroxy-16-heptadecynoic acid. J. Med. Chem. 36, 1418-1424 (1993). |
| | 12(S)-Hydroxy-16-heptadecynoic acid Preparation Products And Raw materials |
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