右旋达尔丰 CAS#: 469-62-5

右旋达尔丰基本信息

中文名称	右旋达尔丰
中文同义词	达尔丰;右丙氧芬;右旋丙氧芬;右旋达尔丰;丙氧芬;右丙氧芬D5;乙腈标准样品
英文名称	Propoxyphene
英文同义词	(+)-PROPOXYPHENE;(+)-1,2-diphenyl-2-propionoxy-3-methyl-4-dimethylaminobutane;(+)-4-(Dimethylamino)-3-methyl-1,2-diphenyl-2-butanol propionate;(+)-4-dimethylamino-1,2-diphenyl-3-methyl-2-propionyloxybutane;(+)-propoxyphen;(2S,3R)-(+)-4-(Dimethylamino)-3-methyl-1,2-diphenyl-2-butanol propionate(ester);(s-(r,s))-te(ester;(s)-alpha-(2-(dimethylamino)-1-methylethyl)-alpha-phenylbenzeneethanolpropanoa
CAS号	469-62-5
分子式	C22H29NO2
分子量	339.48
EINECS号	207-420-5
相关类别
Mol文件	469-62-5.mol
结构式

危险品标志	F,Xn,T
危险类别码	11-20/21/22-36-52/53-25
安全说明	16-26-36/37-61-45-36/37/39
危险品运输编号	3249
WGK Germany	2
危险等级	6.1(b)
包装类别	III
毒害物质数据	469-62-5(Hazardous Substances Data)
毒性	An opioid analgesic similar in structure to methadone. It is a much less potent analgesic than morphine and is devoid of antipyretic or anti-inflammatory effects. Its side effects are qualitatively similar to codeine. The clinical indications for propoxyphene are much the same as for aspirin. It is used when the degree of analgesia required is less than that produced by morphine. Recent clinical trials suggest that propoxyphene is no more effective in controlling mild pain than is aspirin. Because they act by different mechanisms, aspirin and propoxyphene have often been given in combination. Recently, there has been a trend away from use of propoxyphene because its weak analgesic properties do not compensate for other problems with its use. Interestingly, the analgesic activity of propoxyphene resides largely in the dextrorotatory isomer, whereas the antitussive effect is produced primarily by the levorotatory isomer. The use of propoxyphene was banned in the United States in November 2010. The oral LD50 in rats is 84 mg/kg.