盐酸环丙沙星(一水物)
| 中文名称 | 盐酸环丙沙星(一水物) |
|---|---|
| 中文同义词 | 盐酸环丙沙星欧洲药典标准品;环丙沙星盐酸;环丙沙星HCL;盐酸环丙沙星水合物;CIPROFLOXACIN HCL 盐酸环丙沙星;1-环丙基-6-氟-1,4-二氢-4-氧代-7-(1-哌嗪基)-3-喹啉羧酸盐酸盐·一分子水;盐酸环丙沙星(标准品);盐酸环丙沙星(一水物)溶液,100PPM |
| 英文名称 | Ciprofloxacin hydrochloride hydrate |
| 英文同义词 | 3-QUINOLINECARBOXYLIC ACID HYDROCHLORIDE;CIPROFLOXACIN HCL/ CIPROFLOXACIN MONOHYDROCHLORIDE;CIPROFLOXACIN HCL USP;CIPROFLOXACINHYDROCHLORIDE,USP;oride Monohydrate;1-cyclopropyl-6-fluoro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid hydrate hydrochloride;1-Cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid hydrochloride hydrate;Ciprofloxacin hydrochloride hydrate |
| CAS号 | 86393-32-0 |
| 分子式 | C17H21ClFN3O4 |
| 分子量 | 385.82 |
| EINECS号 | 617-845-1 |
| 相关类别 | 生命科学标准品;医药原料;中间体;抗生素类药物;其它抗生素类药;抗生素;兽药;四环素类;分析标准品;原料药;兽药类;医药兽药;原料中间体-原料药;兽药原料药;农用兽用原料;Active Pharmaceutical Ingredients;Quinolones (Antibiotics for Research and Experimental Use);Antibiotics for Research and Experimental Use;Biochemistry;Antibiotic Explorer;Peptide Synthesis/Antibiotics;Pharmaceutical raw materials;原料;医药原料药;化工材料;化工原料;化工中间体;有机化工原料;化学试剂;日用化学品;医用原料;通用生化试剂-抗生素;有机原料;对照品 |
| Mol文件 | 86393-32-0.mol |
| 结构式 |  |
盐酸环丙沙星(一水物) 性质
| 熔点 | 318-320 °C |
|---|---|
| RTECS号 | VB1993800 |
| 储存条件 | Inert atmosphere,Store in freezer, under -20°C |
| 溶解度 | 易溶于水，微溶于甲醇，极微溶于无水乙醇，几乎不溶于丙酮、乙酸乙酯和二氯甲烷。 |
| 形态 | 固体 |
| 颜色 | 白色至浅黄色至浅橙色 |
| PH值 | pH (25g/l, 25℃) 3.0～4.5 |
| 水溶解性 | Soluble in water (35mg/ml). |
| Merck | 14,2314 |
| 主要应用 | pharmaceutical (small molecule) |
| InChI | 1S/C17H18FN3O3.ClH.H2O/c18-13-7-11-14(8-15(13)20-5-3-19-4-6-20)21(10-1-2-10)9-12(16(11)22)17(23)24;;/h7-10,19H,1-6H2,(H,23,24);1H;1H2 |
| InChIKey | DIOIOSKKIYDRIQ-UHFFFAOYSA-N |
| SMILES | O.Cl.OC(=O)C1=CN(C2CC2)c3cc(N4CCNCC4)c(F)cc3C1=O |
| CAS 数据库 | 86393-32-0(CAS DataBase Reference) |
Ciprofloxacin (hydrochloride monohydrate) is a fluoroquinolone antibiotic, exhibiting potent antibacterial activity. Ciprofloxacin (hydrochloride monohydrate) (CIP) shows potent activity against Y. pestis with MIC 90 of 0.03 μg/mL.
Ciprofloxacin (hydrochloride monohydrate) (1 mg/L) induces glutathione-S-transferase (GST) activity, in contrast with inhibited GST and Catalase (CAT) of larvae exposed to enrofloxacin. Ciprofloxacin (hydrochloride monohydrate) (≥10 μg/L) is ecotoxic for development, growth, detoxifying, and oxidative stress enzymes in anuran amphibian larvae. In a murine model of pneumonic plague, Ciprofloxacin (hydrochloride monohydrate) (30 mg/kg, i.p.) results in a drug exposure which is similar to the drug exposure observed in human following a 500 mg dose of oral Ciprofloxacin (hydrochloride monohydrate). Intraperitoneal Ciprofloxacin (hydrochloride monohydrate) reduces the lung bacterial load compare to controls treated with intraperitoneal PBS.
安全信息
| WGK Germany | 3 |
|---|---|
| 危险等级 | IRRITANT |
| 海关编码 | 2933595960 |
| 存储类别 | 11 - 可燃固体 |
| 更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
|---|---|---|---|---|---|
| 2025/12/22 | C2227 | 环丙沙星盐酸盐一水合物 Ciprofloxacin Hydrochloride Monohydrate | 86393-32-0 | 5G | 220元 |
| 2025/12/22 | C2227 | 环丙沙星盐酸盐一水合物 Ciprofloxacin Hydrochloride Monohydrate | 86393-32-0 | 25G | 350元 |