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J & K SCIENTIFIC LTD.
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Product Name:5β-Dihydrocortisol CAS:1482-50-4 Package:100Mg,1g
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| | 11-BETA,17-ALPHA,21-TRIHYDROXY-5-BETA-PREGNANE-3,20-DIONE Basic information |
| Product Name: | 11-BETA,17-ALPHA,21-TRIHYDROXY-5-BETA-PREGNANE-3,20-DIONE | | Synonyms: | 11,17,21-trihydroxy-,(5beta,11beta)-pregnane-20-dione;11-beta,17,21-trihydroxy-5-beta-pregnane-20-dione;11-beta,17,21-trihydroxy-5-beta-pregnane-3,20-dione;11-BETA,17-ALPHA,21-TRIHYDROXY-5-BETA-PREGNANE-3,20-DIONE;5-BETA-PREGNAN-11-BETA, 17,21-TRIOL-3,20-DIONE;5BETA-PREGNAN-11BETA,17ALPHA,21-TRIOL-3,20-DIONE;5-BETA-DIHYDROCORTISOL;5B-pregnane-11B-17A-21-triol-3-20-dione | | CAS: | 1482-50-4 | | MF: | C21H32O5 | | MW: | 364.48 | | EINECS: | | | Product Categories: | Pharmaceuticals, Intermediates & Fine Chemicals, Steroids | | Mol File: | 1482-50-4.mol |  |
| | 11-BETA,17-ALPHA,21-TRIHYDROXY-5-BETA-PREGNANE-3,20-DIONE Chemical Properties |
| Melting point | >173°C (dec.) | | Boiling point | 544.5±50.0 °C(Predicted) | | density | 1.249±0.06 g/cm3(Predicted) | | storage temp. | Refrigerator | | solubility | DMSO (Slightly), Methanol (Slightly) | | form | Solid | | pka | 12.50±0.70(Predicted) | | color | White to Off-White |
| | 11-BETA,17-ALPHA,21-TRIHYDROXY-5-BETA-PREGNANE-3,20-DIONE Usage And Synthesis |
| Uses | 5β-Dihydrocortisol, is a derivative of Cortisol (H714615), which is a steroid hormone, more specifically a glucocorticoid, produced by the zona fasciculata of the adrenal gland. | | Definition | ChEBI: 5beta-dihydrocortisol is a 17alpha-hydroxy-C21-steroid that is cortisol in which the 4-5 double bond has undergone formal hydrogenation to give the corresponding 5beta- steroid. It is a 21-hydroxy steroid, a 17alpha-hydroxy-C21-steroid, an 11beta-hydroxy steroid, a 3-oxo-5beta-steroid, a primary alpha-hydroxy ketone, a triol, a secondary alcohol, a diketone, a 20-oxo steroid and a tertiary alpha-hydroxy ketone. | | in vivo | 5β-Dihydrocortisol (0.1-1.0%; 18 d) potentiates the action of topically applied Dexamethasone (0.06%) in raising the intraocular pressure (IOP) in young rabbits[3]. |
| | 11-BETA,17-ALPHA,21-TRIHYDROXY-5-BETA-PREGNANE-3,20-DIONE Preparation Products And Raw materials |
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