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N-Desethylsunitinib hydrochloride manufacturers
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| | N-Desethylsunitinib hydrochloride Basic information |
| Product Name: | N-Desethylsunitinib hydrochloride | | Synonyms: | N-Desethylsunitinib hydrochloride;N-Desethyl sunitinib HCl;N Desethylsunitinib hydrochloride,NDesethylsunitinib hydrochloride;N-Desethylsunitinib hydrochloride, 10 mM in DMSO;N-Desethylsunitinib hydrochloride (Standard) | | CAS: | 1261432-05-6 | | MF: | C20H24ClFN4O2 | | MW: | 406.89 | | EINECS: | | | Product Categories: | | | Mol File: | 1261432-05-6.mol |  |
| | N-Desethylsunitinib hydrochloride Chemical Properties |
| form | Solid | | color | Yellow to brown |
| | N-Desethylsunitinib hydrochloride Usage And Synthesis |
| Uses | (E/Z)-N-Desethylsunitinib hydrochloride ((E/Z)-SU-12662 hydrochloride) is a compound with potential anti-tumor activity that inhibits VEGF-R2 and PDGF-Rβ tyrosine kinases. (E/Z)-N-Desethylsunitinib hydrochloride is the main active metabolite of sunitinib and has the ability to competitively inhibit ATP[1]. | | References | [1] Discovery of 5-[5-fluoro-2-oxo-1,2- dihydroindol-(3Z)-ylidenemethyl]-2,4- dimethyl-1H-pyrrole-3-carboxylic acid (2-diethylaminoethyl)amide, a novel tyrosine kinase inhibitor targeting vascular endothelial and platelet-derived growth factor receptor tyrosine kinase DOI:10.1021/jm0204183 |
| | N-Desethylsunitinib hydrochloride Preparation Products And Raw materials |
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