| Company Name: |
BOC Sciences |
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1-631-485-4226; 16314854226 |
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info@bocsci.com |
PPDA manufacturers
- PPDA
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2026-05-12
- CAS:684283-16-7
- Purity:
- Supply Ability: 10g
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| Product Name: | PPDA | | Synonyms: | PPDA;(2S*,3R*)-1-(Phenanthren-2-carbonyl)piperazine-2,3-dicarboxylicacid;2,3-Piperazinedicarboxylic acid, 1-(2-phenanthrenylcarbonyl)-, (2R,3S)-rel-;cis-PPDA, GluN2C/GluN2D NMDA antagonist | | CAS: | 684283-16-7 | | MF: | C21H18N2O5 | | MW: | 378.38 | | EINECS: | | | Product Categories: | | | Mol File: | 684283-16-7.mol |  |
| Melting point | 223-226 °C (decomp) | | Boiling point | 730.8±60.0 °C(Predicted) | | density | 1.437±0.06 g/cm3(Predicted) | | storage temp. | Store at +4°C | | solubility | Soluble to 50 mM in 2eq. NaOH and to 100 mM in DMSO | | form | Powder | | pka | 1.73±0.40(Predicted) | | color | White |
| Uses | PPDA is a subtype-selective NMDA receptor antagonist that preferentially binds to NR2C/NR2D containing receptors[1]. | | Definition | ChEBI: (2S,3R)-PPDA is a 1-(phenanthren-2-ylcarbonyl)piperazine-2,3-dicarboxylic acid that has 2S,3R-configuration. It has a role as a NMDA receptor antagonist. It is an enantiomer of a (2R,3S)-PPDA. | | storage | +4°C | | References | [1] Kinarsky L, et al. Identification of subunit- and antagonist-specific amino acid residues in the N-Methyl-D-aspartate receptor glutamate-binding pocket. J Pharmacol Exp Ther. 2005 Jun;313(3):1066-74. DOI:10.1124/jpet.104.082990 |
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