CNQX

CNQX Suppliers list

Company Name:	Capot Chemical Co.,Ltd.
Tel:	+86-（0）57185586718 +86-13336195806
Email:	sales@capot.com
Products Intro:	Product Name:7-Nitro-2,3-dioxo-2,3-dihydroquinoxaline-6-carbonitrile CAS:115066-14-3 Purity:98%(Min,HPLC) Package:100g;1kg;5kg,10kg,25kg,50kg

Company Name:	TargetMol Chemicals Inc.
Tel:	+1-781-999-5354; +17819995354
Email:	marketing@targetmol.com
Products Intro:	Product Name:CNQX CAS:115066-14-3 Purity:>=95% Package:5mg;41USD\|10mg;57USD\|25mg;124USD Remarks:REAGENT;FOR LABORATORY USE ONLY

Company Name:	HANGZHOU CLAP TECHNOLOGY CO.,LTD
Tel:	86-571-88216897,88216896 13588875226
Email:	sales@hzclap.com
Products Intro:	Product Name:CNQX CAS:115066-14-3 Purity:99% Package:10kg 25kg 200 kilograms per barrel Remarks:good

Company Name:	AFINE CHEMICALS LIMITED
Tel:	+86-571-85134551
Email:	info@afinechem.com
Products Intro:	Product Name:6-CYANO-7-NITROQUINOXALINE-2,3-DIONE CAS:115066-14-3 Purity:98%+ Package:Standard or custom package Remarks:excellent quality and reliable supplier

Company Name:	Zhejiang J&C Biological Technology Co.,Limited
Tel:	+1-2135480471 +1-2135480471;
Email:	sales@sarms4muscle.com
Products Intro:	Product Name:CNQX CAS:115066-14-3 Purity:99% Package:5KG;1KG Remarks:CNQX

CNQX manufacturers

CNQX Basic information

Product Name:	CNQX
Synonyms:	7-Nitro-2,3-dioxo-2,3-dihydroquinoxaline-6-carbonitrile;6-CYANO-7-NITROQUINOXALINE-2,3 (1H,4H)-DIONE;CNQX;CNQX 2NA;CNQX DISODIUM SALT;FG-9065;CNQX DISODIUM KAINATE/AMPA RECEPTOR;CNQX (FG-9065) (6-CYANO-7-NITROQUINO
CAS:	115066-14-3
MF:	C9H4N4O4
MW:	232.15
EINECS:
Product Categories:	Heterocyclic Compounds;Neurochemicals;Glutamate receptor;Glutamate;Aromatics;Heterocycles
Mol File:	115066-14-3.mol

CNQX Chemical Properties

Melting point	300 °C
Boiling point	374.31°C (rough estimate)
density	1.5507 (rough estimate)
refractive index	1.6590 (estimate)
RTECS	VD1520000
storage temp.	protect from light
solubility	H₂O: 10 mg/mL
form	solid
pka	8.16±0.20(Predicted)
color	orange to red
Water Solubility	H2O: >2mg/mL (warmed)
Stability:	Store Tightly Sealed at RT
InChI	1S/C9H4N4O4/c10-3-4-1-5-6(2-7(4)13(16)17)12-9(15)8(14)11-5/h1-2H,(H,11,14)(H,12,15)
InChIKey	RPXVIAFEQBNEAX-UHFFFAOYSA-N
SMILES	[O-][N+](=O)c1cc2NC(=O)C(=O)Nc2cc1C#N
CAS DataBase Reference	115066-14-3(CAS DataBase Reference)

Safety Information

MSDS Information

Provider	Language
SigmaAldrich	English
ACROS	English

CNQX Usage And Synthesis

Chemical Properties	Pale Yellow Solid
Uses	CNQX is a competitive, non-NMDA glutamate receptor antagonist (IC50s = 0.3 and 1.5 μM for AMPA and kainate receptors, respectively, versus IC50 = 25 μM for NMDA receptors). This compound has been used to specifically target AMPA and kainate receptor responses and thus differentiate from that of NMDA receptors.
Uses	CNQX disodium salt hydrate has been used as: as a competitive non-NMDA receptor antagonist and competitive AMPA/kainate receptor antagonist in neuronal cultures(110) as a glutamatergic blockers for measuring inhibitory postsynaptic currents in projection neurons(111) as a AMPA glutamate receptor antagonist prefrontal cortex neurons(112)
Uses	A potent, competitive kainate/quisqualate (non-NMDA) receptor antagonist. IC50 of tritiated ligands to rat cortical membranes by CNQX: AMPA, Kainate and CPP are 0.3mM, 1.5mM, and 25mM, respectively
Definition	ChEBI: 6-Cyano-7-nitroquinoxaline-2,3-dione is a quinoxaline derivative.
Biological Activity	Potent AMPA/kainate receptor antagonist. Also antagonist at glycine modulatory site on NMDA receptor complex.
Biochem/physiol Actions	Potent, competitive AMPA/kainate glutamate receptor antagonist.
storage	Room temperature

CNQX Preparation Products And Raw materials

Tag:CNQX(115066-14-3) Related Product Information

2-Nitrobenzonitrile N,N'-Dimethyloxalamide 2-HYDROXY-6-METHYLQUINOXALINE 3-Methyl-4-nitroaniline 1,2,3,4-TETRAHYDRO-QUINOXALINE 4-ACETAMIDOBENZONITRILE 2,3-DIHYDROXYQUINOXALINE 3,4-Diaminobenzonitrile 4-ACETAMIDO-2-METHYLNITROBENZENE 6-NITROQUINOXALINE-2,3-DIONE 2,5-Diaminobenzonitrile 1,4-DIHYDRO-6-METHYLQUINOXALINE-2,3-DIONE 6-NITRO-1,2,3,4-TETRAHYDRO QUINOXALINE 4-(N-Methylamino)benzonitrile CNQX N'-METHYL-4-NITROPHENYLENEDIAMINE-(1,2) PYRAZINE-2,3-DIOL N-(4-amino-3-methylphenyl)acetamide