|
|
| | 4-(3,4-Dichlorophenyl)-5-(4-pyridinyl)-2-thiazolamine Basic information |
| Product Name: | 4-(3,4-Dichlorophenyl)-5-(4-pyridinyl)-2-thiazolamine | | Synonyms: | CGH 2466 DIHYDROCHLORIDE;4-(3,4-Dichlorophenyl)-5-(4-pyridinyl)-2-thiazolaminedihydrochloride;4-(3,4-Dichloro-phenyl)-5-pyridin-4-yl-thiazol-2-ylamine;2-Thiazolamine, 4-(3,4-dichlorophenyl)-5-(4-pyridinyl)-;4-(3,4-Dichlorophenyl)-5-(4-pyridinyl)-2-thiazolamine | | CAS: | 252198-68-8 | | MF: | C14H9Cl2N3S | | MW: | 322.21 | | EINECS: | | | Product Categories: | | | Mol File: | 252198-68-8.mol |  |
| | 4-(3,4-Dichlorophenyl)-5-(4-pyridinyl)-2-thiazolamine Chemical Properties |
| storage temp. | Desiccate at +4°C |
| | 4-(3,4-Dichlorophenyl)-5-(4-pyridinyl)-2-thiazolamine Usage And Synthesis |
| Definition | ChEBI: CGH 2466 is a member of thiazoles. | | Biological Activity | Adenosine A 1 , A 2B and A 3 receptor antagonist (IC 50 values are 19, 21, and 80 nM respectively). Also inhibits p38 MAPK (IC 50 = 187-400 nM) and phosphodiesterase type 4D (IC 50 = 22 nM). Displays potent anti-inflammatory effects in vitro and in vivo . Potentially useful for asthma and chronic obstructive pulmonary disease (COPD) research. |
| | 4-(3,4-Dichlorophenyl)-5-(4-pyridinyl)-2-thiazolamine Preparation Products And Raw materials |
|