Loe 908 hydrochloride

Loe 908 hydrochloride Suppliers list
Company Name: 3B Pharmachem (Wuhan) International Co.,Ltd.  
Tel: 18930552037
Email: 3bsc@sina.com
Company Name: BOC Sciences  
Tel: 1-631-485-4226; 16314854226
Email: info@bocsci.com
Company Name: Beijing HuaMeiHuLiBiological Chemical   
Tel: 010-56205725
Email: waley188@sohu.com
Company Name: EMMX Biotechnology LLC  
Tel: 888-539-0666
Email: info@emmx.com
Company Name: Shanghai EFE Biological Technology Co., Ltd.  
Tel: 021-65675885 18964387627
Email: info@efebio.com

Loe 908 hydrochloride manufacturers

  • Pinokalant
  • Pinokalant pictures
  • $195.00
  • 2026-07-27
  • CAS:149759-26-2
  • Purity: 98.04%
  • Supply Ability: 10g
Loe 908 hydrochloride Basic information
Product Name:Loe 908 hydrochloride
Synonyms:LOE 908;3,4-Dihydro-6,7-dimethoxy-α-phenyl-N,N-bis[2-(2,3,4-trimethoxyphenyl)ethyl]-1-isoquinolineacetamidehydrochloride;Pinokalant;1-Isoquinolineacetamide, 3,4-dihydro-6,7-dimethoxy-α-phenyl-N,N-bis[2-(2,3,4-trimethoxyphenyl)ethyl]-;Loe 908 hydrochloride
CAS:149759-26-2
MF:C41H48N2O9
MW:712.83
EINECS:
Product Categories:
Mol File:149759-26-2.mol
Loe 908 hydrochloride Structure
Loe 908 hydrochloride Chemical Properties
Boiling point 803.7±65.0 °C(Predicted)
density 1.17±0.1 g/cm3(Predicted)
storage temp. Desiccate at RT
form Solid
pka5.47±0.20(Predicted)
color Off-white to light yellow
Safety Information
MSDS Information
Loe 908 hydrochloride Usage And Synthesis
UsesLOE 908 Hydrochloride is a isoquinoline derivative and a cation channel blocker. LOE 908 Hydrochloride is a neuroprotective agent.
Biological ActivityBroad spectrum cation channel blocker. Inhibits several cation channels including store-operated calcium channels (SOCs), voltage-operated calcium channels (VOCs), non-selective cation channels (NSCCs), AMPA, NMDA, Na + and K + channels. Neuroprotective; reduces cortical infarct size and improves neurological outcome following middle cerebral artery occlusion.
in vivo

Pinokalant significantly reduces cortical infarct volume from 33.8 mm3 to 24.5 mm3[1].

Loe 908 hydrochloride Preparation Products And Raw materials
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