5H-Thiazolo[3,2-a]pyrimidine-6-carboxylic acid, 3,7-dimethyl-5-phenyl-, ethyl ester

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5H-Thiazolo[3,2-a]pyrimidine-6-carboxylic acid, 3,7-dimethyl-5-phenyl-, ethyl ester Basic information
Product Name:5H-Thiazolo[3,2-a]pyrimidine-6-carboxylic acid, 3,7-dimethyl-5-phenyl-, ethyl ester
Synonyms:5H-Thiazolo[3,2-a]pyrimidine-6-carboxylic acid, 3,7-dimethyl-5-phenyl-, ethyl ester;Tyrosinase-IN-20
CAS:1024364-57-5
MF:C17H18N2O2S
MW:314.4
EINECS:
Product Categories:
Mol File:1024364-57-5.mol
5H-Thiazolo[3,2-a]pyrimidine-6-carboxylic acid, 3,7-dimethyl-5-phenyl-, ethyl ester Structure
5H-Thiazolo[3,2-a]pyrimidine-6-carboxylic acid, 3,7-dimethyl-5-phenyl-, ethyl ester Chemical Properties
Melting point 242-243 °C(Solv: ethanol (64-17-5); acetone (67-64-1))
Boiling point 443.2±55.0 °C(Predicted)
density 1.24±0.1 g/cm3(Predicted)
pka0.65±0.70(Predicted)
Safety Information
MSDS Information
5H-Thiazolo[3,2-a]pyrimidine-6-carboxylic acid, 3,7-dimethyl-5-phenyl-, ethyl ester Usage And Synthesis
UsesTyrosinase-IN-20 (compound 6a) is a potent inhibitor of Tyrosinase with an IC50 of 28.50 μM[1].
References[1] Ghasemi N, et al. Thiazolopyrimidine derivatives as novel class of small molecule tyrosinase inhibitor. BMC Chem. 2023 Nov 19;17(1):156. DOI:10.1186/s13065-023-01077-z
5H-Thiazolo[3,2-a]pyrimidine-6-carboxylic acid, 3,7-dimethyl-5-phenyl-, ethyl ester Preparation Products And Raw materials
Tag:5H-Thiazolo[3,2-a]pyrimidine-6-carboxylic acid, 3,7-dimethyl-5-phenyl-, ethyl ester(1024364-57-5) Related Product Information
Ethyl 7-methyl-3,5-diphenyl-5H-[1,3]thiazolo-[3,2-a]pyrimidine-6-carboxylate ethyl 4-methyl-6-(3-methylphenyl)-2-sulfanyl-1,6-dihydropyrimidine-5-carboxylate 6-(ETHOXYCARBONYL)-5-(4-FLUOROPHENYL)-7-METHYL-2,3-DIHYDRO-5H-[1,3]THIAZOLO[3,2-A]PYRIMIDIN-8-IUM BROMIDE 6-(ETHOXYCARBONYL)-7-METHYL-5-PHENYL-2,3-DIHYDRO-5H-[1,3]THIAZOLO[3,2-A]PYRIMIDIN-8-IUM BROMIDE 5H-Thiazolo[3,2-a]pyrimidine-6-carboxylic acid, 3,7-dimethyl-5-phenyl-, ethyl ester 5H-Thiazolo[3,2-a]pyrimidine-6-carboxylic acid, 5-(4-chlorophenyl)-2,3-dihydro-7-methyl-, methyl ester, hydrobromide (1:1)