| Company Name: |
LGM Pharma |
| Tel: |
1-(800)-881-8210 |
| Email: |
inquiries@lgmpharma.com |
|
| | Dexketoprofen trometamol Basic information |
| Product Name: | Dexketoprofen trometamol | | Synonyms: | D-ketoprofen troMethaMine;(S)-Ketoprofen Tromethamine Salt (Dexketoprofen Trometamol);(S)-(+)-Form tromethamine salt;Dexketoprofen Trometamol Tablets;Dexketoprofen Trometamol（Ketorolac,KETOROL,Ketanov, TORADOL, Toratex, Tromethamine）;2-amino-2-(hydroxymethyl)propane-1,3-diol,2-(3-benzoylphenyl)propanoic acid;dexketoprofen trometamol;2-amino-2-(hydroxymethyl)-1,3-propanediol (s)-3-benzoyl-alpha-methylbenzeneacetate | | CAS: | 156604-79-4 | | MF: | C20H25NO6 | | MW: | 375.42 | | EINECS: | 605-065-4 | | Product Categories: | API;Other APIs;156604-79-4 | | Mol File: | 156604-79-4.mol |  |
| | Dexketoprofen trometamol Chemical Properties |
| Melting point | 104.8-105.1° | | alpha | D20 -5.2° (c = 1.47 in methanol) | | storage temp. | 2-8°C | | solubility | DMSO, Ethanol (Slightly), Methanol (Sparingly) | | form | Solid | | color | White to Off-White | | Major Application | pharmaceutical small molecule | | InChI | InChI=1/C16H14O3.C4H11NO3/c1-11(16(18)19)13-8-5-9-14(10-13)15(17)12-6-3-2-4-7-12;5-4(1-6,2-7)3-8/h2-11H,1H3,(H,18,19);6-8H,1-3,5H2/t11-;/s3 | | InChIKey | QUZMDHVOUNDEKW-XAAIUDFWNA-N | | SMILES | C(N)(CO)(CO)CO.C(C1C=CC=CC=1)(C1C=CC=C([C@H](C)C(=O)O)C=1)=O |&1:20,r| |
| WGK Germany | WGK 3 | | HS Code | 2922199695 | | Storage Class | 11 - Combustible Solids |
| | Dexketoprofen trometamol Usage And Synthesis |
| Uses | Dexketoprofen Trometamol is an non-steroidal anti-inflammatory drug used for the treatment of mild to moderate pain. | | Uses | Mild to moderate pain Musculo-skeltal pain Dysmenorrhea Dental pain | | Synthesis | In dextroketoprofen were added anhydrous ethanol, ethyl acetate and aminobutanetriol, the weight ratio of dextroketoprofen: anhydrous ethanol: ethyl acetate: aminobutanetriol = 1: 2: 7: 0.48, stirring, reflux for 30 minutes, filtered to the crystallization tank while still hot, condensate to 28 ~ 32 , open ice brine down to 10 below the static 3 hours, centrifugation, the cake was washed 2 times with 1 wt. anhydrous ethanol and 7 wt. ethyl acetate mixed solution, centrifugation, filtrate distillation recovery, the cake was dried at 50 for 10 hours, crushed, that is, the dextroketoprofen. The filter cake is washed with 1 wt. of anhydrous ethanol and 7 wt. of ethyl acetate mixed solution for 2 times, centrifugation, filtrate distillation and recovery, the filter cake is dried at 50 for 10 hours, crushed, that is, the finished product of dextroketoprofen aminobutanetriol. |
| | Dexketoprofen trometamol Preparation Products And Raw materials |
|