- Fendiline
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- $2500.00
-
2026-04-21
- CAS:13042-18-7
- Purity:
- Supply Ability: 10g
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| | Fendiline Basic information |
| Product Name: | Fendiline | | Synonyms: | N-(1-Phenylethyl)-3,3-diphenylpropylamine;3,3-diphenyl-N-(1-phenylethyl)propan-1-amine;Benzenepropanamine, γ-phenyl-N-(1-phenylethyl)- | | CAS: | 13042-18-7 | | MF: | C23H25N | | MW: | 315.45 | | EINECS: | 235-915-6 | | Product Categories: | | | Mol File: | 13042-18-7.mol |  |
| | Fendiline Chemical Properties |
| Boiling point | bp0.3 206-210° | | density | 1.031±0.06 g/cm3(Predicted) | | pka | 9.49±0.28(Predicted) | | Water Solubility | 2.331mg/L(22.5 ºC) |
| | Fendiline Usage And Synthesis |
| Originator | Sensit,Thiemann,W. Germany,1974 | | Definition | ChEBI: 3,3-diphenyl-N-(1-phenylethyl)-1-propanamine is a diarylmethane. | | Manufacturing Process | 21.13 grams of γ,γ-diphenyl-propylamine and 12.01 grams of acetophenone
are hydrogenated in 200 ml of methanol at 55°C and a pressure of 10
atmospheres in the presence of palladium charcoal. On filtration of the
catalyst the solution is concentrated and the remainder is distilled in vacuo at
a pressure of 0.3 Hg mm. The main distillate is collected at 206° to 210°C.
25.38 grams of N-[1'-phenylethyl-(1')]-1,1-diphenyl-propyl-(3)-amine are
obtained.
The product is dissolved in 134 ml of 96% ethanol whereupon 26.8 ml of
concentrated hydrochloric acid and 201 ml of water are added while cooling
with ice-water. The precipitate is filtered off and dried in vacuo at 100°C.
22.98 grams of N-[1'-phenylethyl)-(1')]-1,1-diphenyl-propyl-(3)-amine
hydrochloride are obtained. MP 200° to 201°C. On recrystallization from 285
ml of a 2:1 mixture of water and 96% ethanol the melting point remains
unchanged. | | Therapeutic Function | Coronary vasodilator |
| | Fendiline Preparation Products And Raw materials |
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