2(1H)-Quinazolinone, 4-(2-cyclopropylethynyl)-5,6-difluoro-3,4-dihydro-4-(trifluoromethyl)-, (4S)- manufacturers
- DPC-963
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- $1980.00
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2026-07-27
- CAS:214287-90-8
- Purity:
- Supply Ability: 10g
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| | 2(1H)-Quinazolinone, 4-(2-cyclopropylethynyl)-5,6-difluoro-3,4-dihydro-4-(trifluoromethyl)-, (4S)- Basic information |
| | 2(1H)-Quinazolinone, 4-(2-cyclopropylethynyl)-5,6-difluoro-3,4-dihydro-4-(trifluoromethyl)-, (4S)- Chemical Properties |
| Melting point | 187 °C | | Boiling point | 340.3±42.0 °C(Predicted) | | density | 1.54±0.1 g/cm3(Predicted) | | pka | 7.84±0.40(Predicted) |
| | 2(1H)-Quinazolinone, 4-(2-cyclopropylethynyl)-5,6-difluoro-3,4-dihydro-4-(trifluoromethyl)-, (4S)- Usage And Synthesis |
| Uses | DPC-963 is an oral active non-nucleoside reverse transcriptase inhibitor with the IC50 of 18 nM. DPC-963 can be used for study of HIV[1][2]. | | References | [1] Corbett JW, et al. Expanded-spectrum nonnucleoside reverse transcriptase inhibitors inhibit clinically relevant mutant variants of human immunodeficiency virus type 1. Antimicrob Agents Chemother. 1999;43(12):2893-2897. DOI:10.1128/AAC.43.12.2893 [2] Corbett JW, et al. Inhibition of clinically relevant mutant variants of HIV-1 by quinazolinone non-nucleoside reverse transcriptase inhibitors. J Med Chem. 2000;43(10):2019-2030. DOI:10.1021/jm990580e |
| | 2(1H)-Quinazolinone, 4-(2-cyclopropylethynyl)-5,6-difluoro-3,4-dihydro-4-(trifluoromethyl)-, (4S)- Preparation Products And Raw materials |
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