Benzoic acid, 2-[[2,6-dichloro-4-(3,5-dimethyl-1H-pyrazol-4-yl)phenyl]amino]-

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Benzoic acid, 2-[[2,6-dichloro-4-(3,5-dimethyl-1H-pyrazol-4-yl)phenyl]amino]- manufacturers

  • MUN36378
  • MUN36378 pictures
  • $76.00
  • 2026-08-16
  • CAS:2243736-37-8
  • Purity: 99.70%
  • Supply Ability: 10g
Benzoic acid, 2-[[2,6-dichloro-4-(3,5-dimethyl-1H-pyrazol-4-yl)phenyl]amino]- Basic information
Product Name:Benzoic acid, 2-[[2,6-dichloro-4-(3,5-dimethyl-1H-pyrazol-4-yl)phenyl]amino]-
Synonyms:Benzoic acid, 2-[[2,6-dichloro-4-(3,5-dimethyl-1H-pyrazol-4-yl)phenyl]amino]-;MUN36378;FTO inhibitor 1;2-[[2,6-Dichloro-4-(3,5-dimethyl-4-pyrazolyl)phenyl]amino]benzoic Acid;FTO-in-7;2-{[2,6-dichloro-4-(3,5-dimethyl-1H-pyrazol-4-yl)phenyl]amino}benzoic acid;MUN36378, 10 mM in DMSO
CAS:2243736-37-8
MF:C18H15Cl2N3O2
MW:376.24
EINECS:
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Mol File:2243736-37-8.mol
Benzoic acid, 2-[[2,6-dichloro-4-(3,5-dimethyl-1H-pyrazol-4-yl)phenyl]amino]- Structure
Benzoic acid, 2-[[2,6-dichloro-4-(3,5-dimethyl-1H-pyrazol-4-yl)phenyl]amino]- Chemical Properties
Boiling point 523.0±50.0 °C(Predicted)
density 1.439±0.06 g/cm3(Predicted)
pka3.58±0.36(Predicted)
form Solid
color White to off-white
Safety Information
MSDS Information
Benzoic acid, 2-[[2,6-dichloro-4-(3,5-dimethyl-1H-pyrazol-4-yl)phenyl]amino]- Usage And Synthesis
DescriptionMUN36378 is a FTO inhibitor for treatment of leukemia. This compound was first reported in patent WO 2018157842. This product has no formal name at the moment.
UsesFTO-IN-7 is an inhibitor of FTO. FTO-IN-7 can be used in study Alzheimer's diseases, breast cancers, small-cell lung cancers,a human bone marrow striated muscle cancer, a pancreatic cancer, malignant glioblastoma[1].
References[1] Yang, Caiguang, et al.Preparation of 2-substituted-benzene matrix compounds as FTO inhibitors.China,WO2018157843.2018-09-07.
[2] Liu Z, Duan Z, Zhang D, et al. Structure-Activity Relationships and Antileukemia Effects of the Tricyclic Benzoic Acid FTO Inhibitors. J Med Chem. 2022;65(15):10638-10654. DOI:10.1021/acs.jmedchem.2c00848
Benzoic acid, 2-[[2,6-dichloro-4-(3,5-dimethyl-1H-pyrazol-4-yl)phenyl]amino]- Preparation Products And Raw materials
Tag:Benzoic acid, 2-[[2,6-dichloro-4-(3,5-dimethyl-1H-pyrazol-4-yl)phenyl]amino]-(2243736-37-8) Related Product Information
Benzoic acid, 2-[[2,6-dichloro-4-(3,5-dimethyl-1H-pyrazol-4-yl)phenyl]amino]- FTO-IN-14 4-Quinolinol, 8-fluoro-2-[[3-[3-(1-methylethyl)-1,2,4-oxadiazol-5-yl]-1-piperidinyl]methyl]- 1H-Pyrazole-4-carboxamide, N-[(4-ethylphenyl)methyl]-3,5-dimethyl-1-(phenylmethyl)-N-(3-pyridinylmethyl)- FTO-IN-6 DDO-02267