| Company Name: |
ACROBiosystems |
| Tel: |
13121935750 |
| Email: |
jiaxin.zhao@acrobiosystems.com |
|
| | HUMAN EOTAXIN-2 Chemical Properties |
| storage temp. | −20°C | | form | lyophilized powder |
| WGK Germany | 3 | | HS Code | 3504009000 |
| | HUMAN EOTAXIN-2 Usage And Synthesis |
| Description | CCL24 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 78 amino acids and having a molecular mass of 8.8 kDa.
The CCL24 is purified by proprietary chromatographic techniques. | | Source | Escherichia Coli | | Background | Eotaxin-2, also called MPIF2 & Ckb6, is a novel CC chemokine produced by activated monocytes and T lymphocytes. Eotaxin-2 selectively chemoattracts cells expressing CCR3 including eosinophils, basophils, Th2 T cells, mast cells, and certain subsets of dendritic cells. Furthermore, Eotaxin-2 inhibits the proliferation of multipotential hematopoietic progenitor cells. The mature protein, which includes C-terminal truncation, contains 78 amino acids (92 amino acids for the mouse homolog, without C-terminal truncation).
CCL24 functions as a chemotactic chemokine for resting t-lymphocytes, and eosinophils. CCL24 has lower chemotactic activity for neutrophils but none for monocytes and activated lymphocytes. CCL24 is a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell line and binds to CCR3. |
| | HUMAN EOTAXIN-2 Preparation Products And Raw materials |
|