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| | PROTEIN TYROSINE PHOSPHATASE 1B Basic information |
| Product Name: | PROTEIN TYROSINE PHOSPHATASE 1B | | Synonyms: | ANTI-PTP1B antibody produced in rabbit;MONOCLONAL ANTI-PTP1B antibody produced in mouse;ANTI-PTP1B (N-TERMINAL) antibody produced in rabbit;PROTEIN TYROSINE PHOSPHATASE 1B;PROTEIN TYROSINE PHOSPHATASE 1B HUMAN;PROTEIN TYROSINE PHOSPHATASE 1B, HUMAN, RECOMBINANT, E COLI;PTP-1B, AGAROSE;PROTEIN TYROSINE PHOSPHATASE 1B, AGAROSE | | CAS: | | | MF: | | | MW: | 0 | | EINECS: | | | Product Categories: | protein kinase | | Mol File: | Mol File | ![PROTEIN TYROSINE PHOSPHATASE 1B Structure]() |
| | PROTEIN TYROSINE PHOSPHATASE 1B Chemical Properties |
| storage temp. | −70°C | | form | buffered aqueous solution | | biological source | rabbit | | Specific Activity | ≥20units/mg protein |
| WGK Germany | 1 | | HS Code | 3504009000 | | Storage Class | 10 - Combustible liquids |
| | PROTEIN TYROSINE PHOSPHATASE 1B Usage And Synthesis |
| Uses | Protein Tyrosine Phosphatase 1B (PTP1B) human has been used in treating cell lysate prior to immunoprecipitation and protein pull-down studies. It has also been used in PTP1B activity assay and also for the evaluation of inhibitors like betulinic acid (BA) and sodium orthovanadate (Na3VO4), and 6-chloro-3-formyl-7-methylchromone (CFM) on PTP1B. | | General Description | Protein tyrosine phosphatase 1B human (PTP1B) is encoded by the gene PTPN1. In human chromosome, the gene PTPN1 is localized on 20q13.13. The protein has 37 kDa catalytic domain and the C-terminal hydrophobic residues targets the protein to the cytoplasmic side of the endoplasmic reticulum membrane. | | Biochem/physiol Actions | PTP-1B is a recombinant, non-transmembrane protein expressed in E. coli containing amino acid residues 1-322 of human PTP-1B. It has a molecular mass of 37.4 kDa. It is an abundant intracellular enzyme that is thought to act as a negative regulator of certain signaling pathways. It dephosphorylates tyrosine-phosphorylated proteins and peptides, and is usually localized in the cytostolic domain of the ER. |
| | PROTEIN TYROSINE PHOSPHATASE 1B Preparation Products And Raw materials |
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