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| Product Name: | HUMAN MIP5 (CCL15) | | Synonyms: | Anti-TXNDC5 antibody produced in goat;CCL15;HCC-2;HUMAN MIP5 (CCL15);HUMAN MIP5 (CCL15) CHEMICALLY SYNTHESIZED CHEMOKINE;HUMAN LKN-1;HUMAN MACROPHAGE INFLAMMATORY PROTEIN-5;MIP-5 (HUMAN) | | CAS: | | | MF: | | | MW: | 0 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File | ![HUMAN MIP5 (CCL15) Structure]() |
| | HUMAN MIP5 (CCL15) Chemical Properties |
| | HUMAN MIP5 (CCL15) Usage And Synthesis |
| Description | Macrophage Inflammatory Protein-5 Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 92 amino acids and having a molecular mass of 10.1 kDa. The MIP5 is purified by proprietary chromatographic techniques. | | Source | Escherichia Coli | | Background | CCL15, a new human CC chemokine, was isolated from a human fetal spleen cDNA library. CCL15 cDNA encodes a predicted 113 amino acid (aa) protein containing a putative signal peptide of 21 amino acids that is cleaved to generate a 92 aa residue mature protein. Within the CC family members, human CCL15 shares 45%, 44%, 35%, and 30% aa homology with mouse C10, human MPIF-1, human HCC-1, and mouse MIP-1?, respectively. The gene for MIP-5 is found on chromosome 17 where the genes for most of the human CC chemokines are located. Human CCL15 is expressed in T and B lymphocytes, NK cells, monocytes and monocyte-derived dendritic cells. Human MIP-5 is chemotactic for T cells and monocytes and has been shown to induce calcium flux in human CCR-1-transfected cells. |
| | HUMAN MIP5 (CCL15) Preparation Products And Raw materials |
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