Diproteverine manufacturers
- Diproteverine
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- $2500.00
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2026-05-11
- CAS:69373-95-1
- Purity:
- Supply Ability: 10g
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| | Diproteverine Basic information |
| Product Name: | Diproteverine | | Synonyms: | Diproteverine;1-[(3,4-Diethoxyphenyl)methyl]-3,4-dihydro-6,7-bis(1-methylethoxy)isoquinoline;BRL-40015;1-[(3,4-diethoxyphenyl)methyl]-6,7-di(propan-2-yloxy)-3,4-dihydroisoquinoline | | CAS: | 69373-95-1 | | MF: | C26H35NO4 | | MW: | 425.565 | | EINECS: | | | Product Categories: | | | Mol File: | 69373-95-1.mol |  |
| | Diproteverine Chemical Properties |
| | Diproteverine Usage And Synthesis |
| Uses | Diproteverine (BRL 40015) is an oral activity calcium channel blocker. Diproteverine embryonic toxicity. Diproteverine also shows antianginal properties[1][2]. | | in vivo | Diproteverine (40, 80, 160, 320 mg/kg; p.o.; daily for 10 days) shows embryonic toxicity in rats[1]. | Animal Model: | Sprague-Dawley virgin female rats[1] | | Dosage: | 40, 80, 160, 320 mg/kg | | Administration: | P.o.; daily for 10 days | | Result: | Induced embryonic deaths, significantly increased incidence of fetuses showing an unusual pattern of digital, tail, heart, and vertebral abnormalities. |
| | References | [1] Ridings JE, et al. Prenatal toxicity studies in rats and rabbits with the calcium channel blocker diproteverine. Reprod Toxicol. 1996 Jan-Feb;10(1):43-9. DOI:10.1016/0890-6238(95)02017-9
[2] Lacroix P, et al. Diproteverine (BRL 40015): a new type of calcium antagonist with potential antianginal properties. Eur J Pharmacol. 1991 Jan 17;192(3):317-27. DOI:10.1016/0014-2999(91)90220-k |
| | Diproteverine Preparation Products And Raw materials |
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