| Company Name: |
TargetMol |
| Tel: |
400-821-0310 15002144251 |
| Email: |
xuexiang.shao@tsbiochem.com |
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| | Utibaprilat Basic information |
| Product Name: | Utibaprilat | | Synonyms: | Utibaprilat;(2S)-5-tert-Butyl-3-[(2S)-2-[[(1S)-1-carboxy-3-phenylpropyl]amino]propanoyl]-2,3-dihydro-1,3,4-thiadiazole-2β-carboxylic acid;FPL-63674;Utibaprirat | | CAS: | 109683-79-6 | | MF: | C20H27N3O5S | | MW: | 421.51 | | EINECS: | | | Product Categories: | | | Mol File: | 109683-79-6.mol |  |
| | Utibaprilat Chemical Properties |
| Boiling point | 607.782±65.00 °C(Press: 760.00 Torr)(predicted) | | density | 1.316±0.14 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | | pka | 0.295±0.40(predicted) |
| | Utibaprilat Usage And Synthesis |
| Uses | Utibaprilat (FPL 63674XX) is a ACE inhibitor that is a major degradation product of Utibapril (HY-101681)[1]. | | References | [1] Krier M, et al. Bioisosteric similarity of molecules based on structural alignment and observed chemical replacements in drugs. J Chem Inf Model. 2009 May;49(5):1280-97. DOI:10.1021/ci8003418
[2] Jagota N K, et al. HPLC Determination of Utibapril and its Diacid FPL 63674XX in Rodent Laboratory Diet Using Selective Extraction and Gradient Elution Chromatography. Journal of liquid chromatography, 1991, 14(15): 2979-2991. |
| | Utibaprilat Preparation Products And Raw materials |
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